There is a reason why nutritionists around the world often emphasize the need for essential vitamins. In addition to strengthening us and strengthening our immunity, some of these vitamins also have a healing effect on internal injuries. If the results of a recent study are adopted, oral intake of vitamin B3 could potentially help prevent acute kidney damage affecting 30-40 percent of all hospitalized adults in low-income countries.
Acute kidney damage can be fatal to a few. Doctors and scientists are working to find a specific treatment for the condition. The condition is characterized by excess accumulation of waste products in the blood and an imbalance of fluids throughout the body.
The results published in the journal Nature Medicine showed that the nicotinamide adenine dinucleotide (NAD +) level ̵
We were able to detect a drop in NAD + in the urine of high-risk patients who were either in intensive care or undergoing major surgery and found that oral vitamin B3 can safely increase NAD + in high-risk patients, "said lead investigator Samir M. Parikh, nephrologist and associate professor at Harvard University.
"These results are very early, but the results indicate that one day we could get a non-invasive test for NAD + and maybe even treat acute kidney damage NAD + levels, "he added.
For the study, the team examined the metabolic changes associated with acute kidney injury in a mouse model: a urine screen showed high levels of quinolinate, then created a mouse model with reduced QRPT. an enzyme responsible for the conversion of quinolinate to NAD + – but no kidneys The genetically modified rodents mimicked the pattern of acute kidney injury; decreased NAD +, increased urinary quinolinate, and increased susceptibility to kidney damage. The experiments were the first to establish QRPT as a mediator of renal stress resistance.
In further human studies, the team found high-valent quinolinate in patients undergoing major surgery at risk of acute kidney injury and confirmed a metabolite pattern in a separate study of 329 ICU patients who also had one acute renal failure.
The team administered a high dose of oral vitamin B3 to 41 cardiac surgery patients who participated in a Phase 1 pilot study. Vitamin B3 levels could be safe and potentially beneficial to patients, the researchers claimed.
Vitamin B3 is also popularly known as niacin. It is a very important nutrient because every part of the body needs it to function properly. Vitamin B3 or niacin is primarily used to lower high levels of cholesterol in the body.
Here are some natural sources of vitamin B3 that you can include in your diet; they also come packed with several other health benefits.
. 1 Tuna: Tuna is a powerhouse of essential nutrients such as omega-3 fatty acids, potassium, magnesium, iron, vitamins A, B6 and B12 and is therefore health-promoting
2. Mushrooms: Mushrooms are Low in calories, full of vitamin D and full of healthy antioxidants. You can have them in stews, broths and salads.
3. Avocados: Avocados are a source of omega-3 fatty acids. Avocados can work wonders if you keep your blood pressure under control. Avocados are a good source of folic acid. Pregnant women can include avocados in their diet
4. Green peas: The naturally sweet legume is rich in essential vitamins and antioxidants such as vitamins K, C and folic acid. It is also rich in manganese and fiber.
5. Peanuts: Peanuts like legumes have a lot of protein, healthy fat and are low in carbohydrates. They are also a rich source of minerals including copper, manganese, potassium, calcium, iron, magnesium, zinc and selenium, all of which are essential for maintaining a healthy body.
(with inputs IANS)