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A new vaccine could target aggressive forms of breast cancer, says study



While there is no known cure for breast cancer, scientists are working on medicines that could be key to treating the disease, according to a new report.

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Researcher from the Mayo Clinic recently conducted a study to develop a vaccine that could eliminate cancer cells and possible disease recurrence.

The vaccine helps the body withstand the return of the human epidermal growth factor receptor 2 (HER2), a protein that can cause breast cancer. It should be used with trastuzumab, an immunostimulating drug given to women after HER2 tumor removal. If successful, the researchers believe the vaccine could prevent the cancer from returning and spreading to other parts of the body.

Here's how it works:

Vaccination in combination with trastuzumab works by activating the B cells of the immune system that attack breast tumor cells with HER2. The process then triggers other cell groups to promote resistance to disease recurrence.

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"The vaccine offers a prevention strategy to prevent cancer reform," co-author Keith Knutson said in a statement. "The body's T-cells and B-cells synergize with each other for a strong, lasting immune response."

The analysts found that the drug can cause mild reactions such as fatigue. For future research, they hope to find out how long immunity will last and whether it can be used to attack other cancer cells.

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"The standard approaches to treating cancer address the existing disease," Knutson said. "Our goal is to develop a strategy to handle recurrences, we have good medicines like trastuzumab that can disrupt the recurrence of HER2 breast cancer and we hope that a vaccine that tackles multiple aspects of the body's immune system, build on these achievements. "

The researchers received a US $ 1

1 million grant from the US Department of Defense for further exploration.


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