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A Scottish woman who does not feel pain has a rare gene mutation

She thought little about it until she was treated for a hip problem at the age of 65. The doctors were amazed when she found that she had no pain in the joint despite severe degeneration. A year later, she said she did not feel any pain after undergoing a very painful surgery on her hand for osteoarthritis.

Her doctors decided to analyze whether her lack of sensitivity to pain was genetic and caused by a mutation in a previously unidentified gene.

"Until a few years ago, I had no idea that it was so unusual how little pain I feel, just thinking it was normal," Cameron said in a press release.

A Case Study Published Thursday The researchers said the discovery may help direct new treatments for a range of disorders, from postoperative pain to anxiety.
  Jo Cameron left his family.

"The implications for these findings are immense," Dr. Devjit Srivastava, co-author of the study and consultant for anesthesia and pain medicine in a public hospital in the north of Scotland. He diagnosed Cameron.

"One in two patients still has moderate to severe pain after surgery today, despite all advances in painkillers," he added.

"The results suggest a novel analgesic discovery that could potentially provide support We hope this can help the 330 million patients who are operated on worldwide each year."

Burnt Meat

[19659002] Cameron told the researchers she had a long painless injury. Sometimes she does not notice that she was burned until she smells her singed flesh.

The researchers also found that Cameron was an optimist, with the lowest score on a standard anxiety scale. She said that she never panics even in dangerous situations like a recent traffic event.

The researchers said that it is possible that there are more people with the same mutation because Cameron did not know about their condition until the 1960s.

"People with uncommon sensitivity to pain may be valuable to medical research, as we learn how your genetic mutations affect how they feel pain, so we encourage anyone who is not in pain to move forward come, "said James Cox, senior lecturer at University College London. Jo Cameron, right. Jo Cameron, right. right. "class =" media__image "src =" http://cdn.cnn.com/cnnnext/dam/assets/190328072605-03-woman-feels-no-pain-gene-mutation-large-169.jpg "/> [TheresearchersfoundthatCameronhadtwonotablemutationsintheirgeneticmakeuponeintheFAAHgeneandanotherinwhatthescientistscalledFAAH-OUTwhichhasbeenlittlestudiedbyscientists

"Well, As we know how this newly identified gene works, we hope to make further progress in new treatment goals, "said Cox.

Dr Frances Williams, Professor of Genomic Epidemiology at King's College London, who attended the Research was not involved, calling the study "really important."

She said FAAH "was already the target of several clinical trials," but the latest research tells us more about the FAAH-OUT, which is a "more effective method of creating." painkillers, "she said.

Edmund Keogh, Professor f Psychology at the University of Bath said the pain was "helpful and functional" and differentiated between individuals

"We need to learn from people who suffer from pain, but also from people who are less sensitive to pain," he said Keogh, who is also deputy director of the University Center for Pain Research.

The study indicates that Cameron's mother and daughter normally experience pain as normal. However, her late father hardly needed any painkillers, and her son reported a degree of pain insensitivity, but not as much as she did.

She does not take medications and is fit and active, with no illnesses other than arthritis.

"I would be delighted if exploring my own genetics could help other suffering people," she said.

CNN's Nina Avramova contributed to this report.

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