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Autism and high estrogen levels may be related, researchers suggest



In recent years, a team of Cambridge University researchers has investigated the association between testosterone and autism.

Now, however, new research has revealed that there may be a stronger link between autism and estrogen.

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This study was published this month in Molecular Psychiatry and was published by Dr. med. Simon Baron-Cohen, who is the director of the University for the Autism Research Center.

The same researchers previously saw increased testosterone activity during pregnancy in children who developed autism sm, especially in boys.

Their finding correlates with the higher incidence of autism in male children. According to CDC, boys are 4 times more likely to suffer from this disorder than girls.

However, the current study reports that other studies have not always demonstrated this link between high levels of testosterone and autism. In several studies, for example, the hormone levels were measured after the birth of the child, but a high testosterone level did not correspond to an autism diagnosis.

The researchers therefore found that these findings may indicate an association between ASA and the broader endocrine system

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In this new study, researchers measured estrogen levels using fruit water samples from the Danish birth cohort. The cohort is a large database of samples and information on thousands of pregnancies.

Using these samples, scientists determined estrogen levels in 98 boys who had autism spectrum disorder (ASD) and 1

77 boys who did not.

showed that a high estrogen content has a strong connection with the later development of ASA in a baby.

The authors stated that their method "provided the first evidence that elevated levels of prenatal amniotic estradiol, estriol, and estrone, each associated with autism and estradiol levels, are the most significant predictors of the likelihood of autism. , , , "

This correlation between estrogen and autism could be a new way of exploring the causes of ASD, as the role of estrogen in autism has never been explored, the report says.

However, estrogen, like testosterone, is known to influence brain development

Against this backdrop, scientists have shown that autistic girls have an abnormal brain structure that is detectable by MRI, the report said.

In addition, autistic women and their mothers tend to get breast or ovarian cancer more often than other women. High estrogen levels may explain some of the features that have been observed in autism.

The study concludes that high estrogen is a "feature of autism". The authors believe this hormone might interact with genetic factors that affect the disorder.

However, one important note is that Professor Baron-Cohen and his team are just looking for a deeper understanding of autism, says the professor at Medical Xpress. The team is not trying to set up ASD screening or ASD prevention.


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