PROBIOTICS seem to be everywhere these days – in yogurt, cucumbers, bread, even dog food. But there is one place that might surprise you: there are probiotics in dirty diapers.
Yes, that's right – baby poop.
Wake Forest School of Medicine scientists have developed a probiotic "cocktail" of intestinal bacteria strains in childhood feces that can help increase the body's ability to produce short-chain fatty acids (SCFAs), a recent report said published publication.
Why is that so important?
"Short-chain fatty acids are a key component of good gut health," said Hariom Yadav, scientific director of the study at the Wake Forest School of Medicine. "People with diabetes, obesity, autoimmune diseases and cancer often have fewer short-chain fatty acids, and increasing them can be helpful in maintaining or even rebuilding a normal bowel environment and hopefully improving health."
The press release states Results of the study have been published in the online edition of Scientific Reports a Nature publication
In the last decade, research has shown that specific probiotic strains cause certain diseases in both animal models can also effectively prevent or treat people. These reports have led to an extensive demand for probiotic supplements over the past decade, leading to a massive increase in the development of new probiotic products for the consumer market.
However, these studies were conducted mainly in animal models or humans with underlying diseases or conditions, Yadav said. Scientific reports on the effects of probiotics in healthy, disease-free subjects have remained relatively limited and inconsistent.
The School of Medicine team has designed the study to investigate and determine the effects of probiotic strains from healthy human stool samples.
"Babies are usually quite healthy and do not seem to suffer from age-related diseases such as diabetes and cancer," Yadav said. "And of course her droppings are readily available."
In the study, Yadav's team collected fecal samples from the diapers of 34 healthy infants. After developing a robust protocol for the isolation, characterization and safety testing of Lactobacillus and Enterococcus strains with probiotic properties in the infant intestine, the scientists selected the 1
To test the ability of these human probiotics To modify the gut microbiota – bacteria that live in the digestive tract – and their ability to produce SCFAs, the mice received a single dose and five consecutive doses of this probiotic 10-strain cocktail , The researchers then injected the same probiotic mixture in the same dose into a human feces medium, the publication said.
The scientists found that single- and five-dose feeding of these selected probiotics modulated the gut microbiota and the production of SCFAs in the mouse and human stools
"This work provides evidence that these probiotics are derived from humans could be used as biotherapeutic therapies for human diseases with gut microbiota imbalance and decreased intestinal SCFA production, "Yadav said. "Our data should be useful for future studies aimed at investigating the impact of probiotics on the human microbiome, metabolism and associated diseases."
The publication also suggested that the study was limited in that it did not examine any disease models that probiotic mixture.