The cat was apparently with us forever. A few years ago, a freshly deciphered Egyptian papyrus showed that as early as 1900 years ago, cures were the consequences of consuming too much alcohol in people's minds – the recommended option in this case would be a necklace made from a leather leaf hut.
Several other folklore-suggested treatments include breakfast with pickled herring, a roasted canary (thank you, Romans), salty prunes and the Prairie Oyster, an American concoction of raw eggs, tomato juice, spicy sauce and other fixations. Anything that could cure the throbbing headache, nausea, fatigue, and disorientation that characterizes the hangover was tried.
Apart from the tincture of time, however, very little seems to work. One difficulty in developing hangover treatment is that what a hangover is when it comes to molecular biology is still not well known. Interestingly, hangover symptoms do not occur until the alcohol has already left our blood.
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This suggests that metabolites are involved that are degraded by our bodies. Ethanol is broken down by liver enzymes into acetaldehyde and then broken down into acetate, which turns into fatty acids and water. Some scientists have speculated that acetaldehyde may cause some hangover symptoms, especially given the suggestion that intoxication occurs more quickly in people with mutations that hinder the enzymes that remove it. However, some studies indicate that the acetaldehyde content does not correlate with the severity of the hangover.
Others are not only suspicious, not only because of the alcohol itself or its metabolites, but also what goes with them ̵
Dark alcohol with more of these substances seems to be worse than clear: a 2009 study found that those who drank dark bourbon felt much worse than those who drank vodka. But there is some variation between humans, from basic biology, to hydration, to speed-not to mention age-which many suspect will make it harder to get away from a night of over-indulgence without being disturbed.  In fact, the symptoms of a hangover are probably not due to a single molecule or group of molecules, but to a combination of factors.
Not many studies have carefully considered all of these things, in part because it's difficult to do so. Master everything and naturally imitate how people behave on a lethargic night.
In fact, the hangover symptoms are probably not due to a single molecule or set of molecules, but rather to a combination of factors. Alcohol consumption results in a shift in hormone regulation that can cause people to urinate more so that they can become dehydrated the next day, which helps explain the headache. People often drink at the expense of a full night, and alcohol affects the quality of sleep they get when they go to bed.
Fatigue and confusion can result in part from insufficient sleep or poor sleep. Some researchers have suggested that fuzzy and cognitive impairment of the hangover may result from some immune activation, with higher concentrations of certain inflammatory compounds mentioned. "There are theories that alcoholism is an immune reaction to heavy drinking," says Joris C Verster, a professor at the University of Utrecht, who studies the physiology of hangovers. "Research is currently being conducted on messenger substances of the immune system such as cytokines."
The Internet has many suggestions on what to eat to relieve the pain. Bananas are sometimes bred around as hangovers, with some suggesting that they can replenish nutrients such as potassium that is lost when drinking. But a nutritional deficiency is probably not a cause of hangover, and after a single drinking night, you probably do not have such a deficiency.
Heavy, greasy food – a classic "full English" or diner breakfast spoke as something that can help. However, this seems to be a confused version of the advice, difficult to eat before drinking, so that the intake of alcohol is slowed down. There is no evidence that it will help later.
Some suggest eating eggs on the grounds that they contain an amino acid used in the breakdown of acetaldehyde. This is also a bit fantastic as a hangover. There is no good evidence that consuming this amino acid (which incidentally is also present in other foods) helps with symptoms.
Treating the symptoms with Rest, Water and Aspirin is probably the best treatment for some time to come. Eating a hearty meal in advance and drinking slowly can help to keep the alcohol and other levels of the liver and the rest of the body at a manageable level during the night. The best way to avoid a hangover is not to drink too much. If you need something to motivate you, imagine you would eat a roasted canary while you are nauseating. The only thing worse than the hangover could be the cure.
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