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By Dennis Romero
In Fresno, California, three men bought what they considered cocaine last week. Within two minutes of sniffing the white powder, the men were unconscious, the police said.
One of the three men described in the 20s and 30s died in an overdose on January 7 in a hospital. The other two were treated and released. Five days later, 34-year-old Aris Turner died in Chico, California, about 275 miles north, and twelve others were hospitalized for suspected overdose. And on Monday in Oroville, California, a half-hour drive from Chico, two men and women were treated for overdose. In the case of Fresno, the drugs were classified as "1
As the state of California mostly bypassed it by the middle of the decade, the state had one of the lowest Population Opioid Overdose Death Rates in the Nation – Fentanyl has caused deadly devastation in the Midwest and East Coast, often as a cheap filler or even as a substitute for similar heroin or prescription pain relievers, such as oxycodone Synthetic opioid could begin siege of the nation's most populous state.
"We knew there were many cases on the east coast and the middle United States and that they made their way to the west coast," Farmer told reporters Monday. Well, we can say with certainty that it is here. "
The overdose of synthetic opioids rose 2 017 in California by 44 percent, the last year for which data were available, according to the US Centers for Diseas e Control. According to the CDC, there were 536 deaths from synthetic opioids this year in California. The California Department of Public Health (CDPH) reports that 429 of them were fentanyl-accused.
"We were below the national average for every metric, but the number of fentanyl deaths has been rising steadily year by year," said Dan Ciccarone, a University of California, San Francisco, professor of family and community medicine research to heroin and fentanyl use. "There is something incomprehensible that worries me."
Fentanyl is regulated by the US Drug Enforcement Administration as a Schedule II narcotic, which means that it is used only to a limited extent in hospital settings and is legally used as an anesthetic.
"People will stop breathing or have very limited breathing," said Drs. Patil Armenian, an emergency physician from UCSF Fresno and a medical toxicologist who treated the victims on January 7th. "It is so great that there is a concern that it might be enough to make someone breathe and die in just one exposure."
Two policemen were treated in a hospital and released after an overdose in Chico. They felt sick after being near the drug and 30 to 40 times more effective than heroin. The place of overdose, a home, has been declared a hazardous material scene.
In recent years, according to experts, fentanyl was produced in secret laboratories in China and either smuggled through Mexico or sent directly to users and dealers in the United States states that order it in the dark net.
It is not enough to climb so high that it is easy to smuggle, experts say.
Last year, Ciccarone said before a House Subcommittee hearing on the origin of fentanyl in China. He told representatives that the amount of fentanyl smuggled into the US in 2017 was worth only 10 to 14 oil barrels – enough to kill tens of thousands.
Safe cans are hard to come by, research-based RAND Corporation researcher Bryce Pardo said. The fentanyl equivalent of "two grains of salt" could lead to death, he said. "The problem becomes dosage," said Pardo.
Los Angeles journalist Sam Quinones, author of "Dreamland: The True Tale of America's Opiate Epidemic 2015," said a baggy of dark heroin blended with fentanyl that comes as white powder, "would look like chocolate marmot. "
"You can have small pieces of it or a huge amount," he said. "It all boils down to people not mixing well, and that's what's going on."
It's been going on for 40 years.
The Belgian pharmacologist Paul Janssen of Janssen Pharmaceutica is credited with inventing the drug in 1960, but that did not have much of an impact on the black market in 1979 when two men from Orange County, California, died after taking heroin overdoses ,
The deaths attributed to fentanyl analogues sold as "China" The "white heroin" was the beginning of a series of overdoses in the early eighties in the San Diego, Los Angeles, Riverside and Santa Clara counties arrived.
The Centers for Disease Control says Fentanyl and his cousins are responsible for yet another wave The CDC refers to the recent influx of Street Fentanyl as the "third wave of destruction" that began in 2013 and in 2016 the death of pop star Prince demanded.
Experts believe that cheaper fentanyl in regions of the Nat addiction to other opioids, including heroin and prescription pills.
Ciccarone of UCSF said the wave was allegedly driven and that Fentanyl is being injected into the US market by Mexican drug cartels.
In April, the drug killed three victims in Los Angeles County: Gabriel Dirzo, 34; Gilbert Valenzuela Jr., 41, and Robert Ramirez, 36. According to the medical examiner, acute fentanyl poisoning was alleged.
Two men were prosecuted in Southern California by state prosecutors suspected that Fentanyl had resulted in death. According to a statement by the US attorney in San Diego, the victim was overdosed on October 23, recovered at a hospital, and the next day told his suspected dealer before asking for other drugs that prosecutors claimed he had That night, the authorities said, the woman who was not identified died from a fatal overdose.
If Fentanyl prevails on the California black market, it could signal a postponement of the cartel's strategy, namely Sinaloa's This seems to have the biggest impact on the drug market in Golden State, he said.
In 2017, San Diego County, home to the state's second largest city, reported 155 percent more fentanyl overdose deaths  The city is part of the "Tijuana / San Diego Smuggling Corridor", which is largely controlled by Sinaloa Cartel, according to US Drug E. nforcement administration. Tijuana is also the scene of a bloody drug war, a battle largely fought over the sale of methamphetamine, which is also an increasingly cheap and common street drug in San Diego, the authorities said.
Better known as ecstasy to fake prescription pills, from cocaine to methamphetamine. "We hear that more and more fentanyl is appearing in a wide range of drugs, not just traditional heroin," said Tony Botti, spokesman for the sheriff's office in Fresno County. Some Experts Believe Cartels and Traders May Belong
"You can live days without cocaine," said Quinones, who is working on a new book about the Fentanyl and Meth explosion in America. "Your body can not do without the daily use of this drug, a motivation could be to create a new, dependent customer."
"Soon you will either get corpses or new addicts," said Quinones.  Dennis Romero writes for NBC News and lives in Los Angeles.