Recent research has shown that cannabidiol is effective against Gram-positive bacteria, including those responsible for many severe infections (such as Staphyloccocus aureus and Streptococcus pneumoniae ), whose efficacy is similar is that of established antibiotics like vancomycin or daptomycin. The research will be presented at ASM Microbe, the annual meeting of the American Society for Microbiology.
Cannabidiol, the major non-psychoactive chemical compound derived from cannabis and hemp, has been approved by the FDA for the treatment of some form of epilepsy and is being investigated for a number of other conditions, including anxiety, pain and inflammation. Although there is limited data to suggest that cannabidiol can kill bacteria, the drug has not been thoroughly studied for its antibiotic potential.
A work by dr. In collaboration with Botanix Pharmaceuticals Ltd, an early-stage drug discovery company investigating the topical use of synthetic cannabidiol for a range of skin conditions, cannabidiol has been shown to have remarkable efficacy in killing a variety of Gram-positive bacteria, including bacteria, over others "Given the proven anti-inflammatory effects of cannabidiol, the human safety data available, and the potential for different routes of administration, it is a promising new antibiotic that is worth further study," said Drs. BLASKOVICH. "The combination of inherent antimicrobial activity and the potential to reduce the damage caused by the inflammatory response to infections is particularly attractive." Cannabidiol did not lose efficacy under prolonged exposure conditions resulting in resistance to vancomycin or daptomycin. Cannabidiol has also been effective in destroying biofilms, a physical form of bacterial growth that results in infections that are difficult to treat.
The project was co-funded by Botanix and Innovation Connections, a grant program for the commercialization of new products and processes, and services provided by the Australian Government. The paper will be presented at the annual American Society for Microbiology (ASM Microbe 201