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By Shamard Charles, MD and Ali Galante
The possibility of reduction was added to cravings and anxiety among heroin addicts on the growing list of potential CBD uses.
Researchers at the Mount Sinai Hospital in New York announced on Tuesday that the results of a small study found a promising and unexpected new use of CBD: a reduction in cue-induced desire and anxiety in individuals with heroin abuse in the United States History, indicating a possible role in the fight against heroin addiction.
The study results were published in the American Journal of Psychiatry.
"To address the urgent need for new treatment options for the millions of people and families affected by this epidemic, we have launched a study to evaluate the potential of non-toxic cannabinoids for craving and anxiety among heroin addicts investigate. "Yasmin Hurd, head of the Sinai Sick – Eye Research Institute, said in a statement:" The specific impact of CBD on addictive behavior and anxiety is particularly important in the development of addiction drugs, as environmental factors play a role in causing the most severe relapses and continued drug use ,
Hurd and her team on Mount Sinai previously investigated the effects of CBD in animals on heroin. They found that CBD reduced the tendency of animals to consume heroin in response to drug use and decided to investigate the effects of the drug on humans.
The researchers studied 42 drug-abstinent men and women aged 21 to 18 years 65 – in heroin use disorder. Half of the group that had recently stopped consuming heroin received CBD – 400 mg or 800 mg once daily – and the other half received placebo. Subjects were then subjected to neutral and drug-related referrals over three sessions: immediately after administration, 24 hours after CBD or placebo administration, and seven days after the third and last daily CBD or placebo administration.
They found that to be the case Those who received CBD had significantly less druggedness. They also found that the participants showed less fear when looking at pictures of drug users. In addition, CBD appeared to have a lasting effect – the drug continued to reduce cravings and anxiety for seven days, well beyond the time it is expected to be present in the body.
Vital functions such as skin temperature, blood pressure, heart rate, respiratory rate, and oxygen saturation were obtained at different times during the sessions. To the surprise of the researchers, they discovered that CBD lowers the heart rate and cortisol levels in the saliva, which normally increase when addicts are shown images that cause anxiety. This objective finding underpinned Hurd's idea that CBD could be a promising tool to curb opiate addiction.
"Cravings and anxiety are very subjective effects. One of the things that people can do is trick themselves. That's why we measured their physiological responses. These drugs increase the heart rate and cortisol levels of heroin users, so we know this is not subjective, as heart rate and cortisol levels have dropped with CBD – that's really important, "Hurd told NBC News.
Nevertheless, without further investigation, it is not possible to prove whether the results are due to the sole use of CBD, a combination of factors or other factors.
The number of overdose deaths in 2017 rose to over 70,000, a record high and an increase of nearly 10 percent over the previous year, according to Centers for Disease Control and Prevention. Young adults and adolescents are the most affected by the opioid epidemic. In fact, mortality rates among younger adults have risen so much that they have lowered the life expectancy of the entire US population.
We are too slow to tackle addiction in our society. When the flu comes up and the measles come up, so many people try to help. However, we do not have the same urgency as addiction.
Many experts believe that the need for new alternatives in limited options for non-opioid medications is more important than ever.
"We are in the midst of Danesh Alam, medical director of behavioral health at Northwestern Medicine Central DuPage Hospital, who was not involved in the study. "We've seen results like these from studies in the heroin population in 2015-16. There are many chemicals in marijuana, including CBD, that need further investigation, but the limitations of marijuana research have thrown us back."
Alam notes that doing addiction research raises the challenge of finding pharmacological solutions to addiction. "
" Heroin addiction is difficult to investigate because we can not bring 100 recovering patients to our clinics We often deal with the symptoms of the disease, which occur in three phases: the poisoning phase, the dependency phase, and the relapse phase, "said Alam." CBD can play a role in all three, but we do not know exactly learn about his role in anxiety and addiction in general. "
CBD, the component of marijuana, the people nic It has an inhibitory effect and therefore an anti-anxiety effect, added Alam.
] As the popularity of CBD increases and more research is conducted, its role in curbing addiction could become a more realistic alternative.
"We are too slow to tackle addiction in our society. When the flu comes up and the measles come up, so many people try to help. But we do not have the same urgency in addiction, "Hurd told NBC News.
"A successful, no-titers drug would greatly expand the existing addiction drug toolbox to reduce the growing death toll and enormous health costs.
Previous studies in animals suggest that it may help with anxiety, pain and inflammation. In addition, studies recently published in the Journal of the American Medical Association have shown that in countries where people are allowed to legally consume marijuana, the number of prescribed opioids has decreased significantly, and a lower overdose and death rate compared to states without a legal requirement Opioids are cannabis.
This growing body of research is becoming increasingly popular in the scientific community. CBD may have broad medical value in pain management, addiction medicine and neurology.
"In addition to epilepsy, one thing that has been repeated over and over again is fear," said Hurd. "I do not think this is just drug-related anxiety, I think that's fear in general."
Hurd's team plans to conduct longer, larger studies and imaging studies in humans to test whether CBD use TWITTER & FACEBOOK