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Certain antibiotics can cause an aortic aneurysm, warns the FDA



Fluoroquinolone antibiotics are widely used to treat severe respiratory infections, pneumonia, urinary tract infections and even plague and anthrax exposure. These include medicines sold under the names Ciprofloxacin (Cipro), Gemifloxacin (Factive), Levofloxacin (Levaquin), Moxifloxacin (Avelox), Norfloxacin (Noroxin) and Ofloxacin (Floxin).

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Patients take it orally or by injection.

The drugs can cause an aortic aneurysm, a bulge in an artery that can grow and burst and cause dangerous or deadly bleeding. 19659006] Patients most at risk for aortic aneurysm after taking these antibiotics are the elderly, those with high blood pressure, people who have aorta or other blood vessels blocked, and people with genetic disorders such as Marfan syndrome or Ehlers – Danlos syndrome.
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"Although the Risk o In an aortic aneurysm or dissection, we are twice as likely to suffer from an aortic aneurysm or dissection in patients prescribed a fluoroquinolone drug," said FDA Commissioner Dr. Scott Gottlieb in a statement. "For patients who have an aortic aneurysm or are known to be at risk for an aortic aneurysm, we do not believe that the benefits outweigh this risk and alternative treatment should be considered."

For patients who do not fall into these cases risk categories, fluoroquinolones may still be a good option. They have been helping patients with bacterial infections for over 30 years.

The FDA requires that a warning of these risks be included in prescribing information and patient medication guidance.
In July, the agency sent a message that these drugs could significantly lower blood sugar and negatively impact mental health. In 2016, the FDA said the drugs could have a side effect on muscles, nerves, joints, and the central nervous system, and should be restricted for some simpler infections.

The FDA said that they will continue to monitor for any type of infection new safety concerns related to the antibiotics. "The FDA continues to strive to keep the risk information about these products current and comprehensive, and will continue to update the public," said Gottleib.

If you are in any of these risk categories and are taking any of these antibiotics, experts recommend talking to your doctor about taking the medicine.


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