The police found Burrous after a 911 call about a man who "fainted and might not be breathing" at the Days Inn in Glendale.
The phone call on Thursday afternoon was made by a man who was the news anchor at the time, police said. He told the police Burrous had "possibly overdosed".
Glendale Police Sgt. Dan Suttles told KTLA that the first responders immediately recognized Burrous, "because everyone knows Chris."
Death is being investigated. The Coroner's Office in Los Angeles has not yet issued a report on the cause of death.
Burrous arrived in Los Angeles in 201
"Our thoughts and prayers go to the Burrous family," said KTLA president and general director Don Corsini and news director Jason Ball said in a joint statement.
"Chris loved to share the stories from Southern California and get in touch with our viewers, and many will remember him as a great journalist and wonderful friend." He has kindly contributed to his work and is supported by the entire KTLA community. Family deeply missed
The son of a farmer and a NASA engineer married journalist Mai Do-Burrous in 2003 and has a nine-year-old daughter, according to KTLA.
"There are no words," wrote KTLA reporter and anchor Lynette Romero on Twitter with a photo of her and Burrous on set.
"When we took this picture during our show, I had no idea that it would be ours last time together. You made me laugh until I cried. My tears are now for your sweet little girl, your wife Mai and your lovely parents. We will miss you so … "