Dr Michael Mosley, pictured, said he lost almost 20lbs by going on the 5: 2 diet. 800-calorie diet
In my lifetime, I have seen a number of incredible medical breakthroughs, but there is one more excites me more than that any other.
You have heard of diabetes 2, and you may be aware that rates are rising almost.
Even more concerned the number of people with diabetes, including the half-million-plus people who have been diagnosed with the disease people with pre-diabetes. Never heard of it? Well, that's part of the problem.
A major study in the British Medical Journal suggested that rates of pre-diabetes in England alone tripled in a decade, up from 1
Pre-diabetes means blood sugar levels that are abnormally high, and, although they are not yet in the diabetic range, evidence suggests you are probably going to end up there. Worryingly, unless you've had a blood test, you will not know you have it. Type 2 diabetes causes symptoms as an unquenchable thirst, needing to pee a lot, fatigue and blurred vision.
Having high blood sugar levels, even if they are not diabetic, causes damage. To explain why, first here's a mini science lesson.
When we eat, it is absorbed by the digestive system.
Carbohydrates are broken down into single molecules of sugar. ” class=”blkBorder img-share” />
The first sign of pre-diabetes can be used when someone suffers a heart attack. These molecules are then moved into the bloodstream. Sensing incoming sugar, the body releases a hormone called insulin, which transports sugar from the blood and into cells, where it is used for energy.
On the whole, this is a good thing. However, problems begin when, for a variety of reasons, insulin stops working as well in some people – those with type 2 diabetes, and thus those with pre-diabetes.
hence the term high blood sugar – and causes of all kinds of havoc.
Even in those with pre-diabetes, raised sugar levels cause the blood vessel to become stiffer and less flexible which, in time, leads to heart disease and kidney problems.
A fork in the road … but you can make the right choice
The things that put us at risk of pre-diabetes are the same as those for type 2 diabetes itself.
What does it mean? And the 2 diabetes is up to four times more likely in people of South Asian, African-Caribbean or black African Descent.
The reason for this is not clear, but it has been suggested that the body processes and stores
A pre-diabetes diagnosis can be a fork in the road for people – giving them a time to change their lifestyle
But there are factors we can control. Some people say it's a fork in the road.
Being overweight, especially if you carry around your middle age, is one of the risk factors that can be reduced with lifestyle changes.
I'm a case in point. 7 years ago, thanks to a random blood test, at the age of 56 I had discovered that I had type 2 diabetes. I had probably been pre-diabetic for some years.
Rather than start on tablets, I looked for an alternative solution. That's how I found out about intermittent fasting and invented the 5: 2 diet.
I was, in many ways, fortunate. There is an increase that can be reversed with weight loss. Self-administered injections of the hormone insulin.
One of the pioneers of this approach is Professor Roy Taylor of Newcastle University. I first met Prof Taylor in 2014, soon after I had managed to tackle my own problem.
His research has given us the very best answer tummy, but also inside the abdomen, where it infiltrates the liver and pancreas gland.
These two organs are responsible for controlling our insulin and blood sugar levels. As they get clogged up with fat, they stop communicating with each other.
We have our own personal fat threshold – a tipping point
Your tipping point decides how much you can accumulate before it starts to 'overflow' into the liver and pancreas.
Stop diabetes in its tracks with a low-calorie diet
In my case, going on the 5: The good news is that whatever your personal fat threshold may be, you can reverse the situation.
In my case, going on the 5:
But it turns out to be one of the best ways to reverse pre-diabetes with a rapid-weight-loss 800-calorie diet.
We know this thanks The trial involved 2,326 overweight men and women, who had all had pre- diabetes.
The volunteers were asked to go on an 800-calorie diet for eight weeks, with the aim of losing eight per cent of their body weight. In fact, most of them did better than expected, losing an average of 22 lb.
Along with this loss of fat, they are significantly more in their cholesterol and blood pressure, and nearly half of them managed to get their blood sugars Back to normal healthy levels.
According to Dr Mosley, going on an 800-calorie a day diet can see a 22lb reduction in body weight within eight weeks
Professor Jennie Brand-Miller, of the University of Sydney, one of the lead researchers, said he was more likely to get rid of their pre-diabetes people soon adapt and stop feeling hungry.
It is important, however
It is encouraging, they said, that when the volunteers lost weight, they became more active, which added to the benefits.
So the message is clear. If you are over 40, overweight, and especially if you have a history of diabetes,
You can buy a pre-diabetes kit from chemists or online, or discuss it with your GP.
If you already have diabetes, there is evidence that a similar eight- to 12-week low-calorie diet wants help.
But it is, of course, that it is a problem in the first place. 19659005] Over the following pages, we want to show you how.
We speak with the world's leading experts on just how to play a role.
19659005] delicious and simple low-calorie recipes.
Imagine if, one day, you could predict your risk of pre-diabetes from birth. The knowledge could be life-changing.
Researchers say it could be as simple as giving a blood sample which would be involved in early research be screened for the genes that make diabetes more likely. An international consortium of researchers, including those from Oxford and Dundee universities, are currently analyzing the DNA of hundreds of thousands of people who have already had pre-diabetes or type 2.
By following them how to see their conditions progress, it is
 Those who are at risk of pre-diabetes but not type 2, those who will inevitably progress from pre-diabetes to type 2, and those who want
Crucially, it could not lead to being able to do well.
Professor Calum Sutherland, of Dundee University, says: 'In theory, we should not be able to spot cases before emerge, because the genes are there from birth.
' We're not there yet. But the diabetes prevention programs are heavily biased toward BMI readings, and many of those people may not get type 2 in the next ten years. Other higher-risk people could use. '