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Deadly superbug outbreak in humans linked to antibiotic spike in cows



 Deadly superbug outbreak in humans linked to antibiotic spike in cows

A deadly outbreak of multi-drug resistant Salmonella That sickened 225 people across the US beginning in 2018 may have been spurred on by a sharp rise in the use of certain antibiotics in cows a year earlier, infectious disease investigators reported this week.

From June 201

8 to March of 2019, officials at the Centers for Disease Control and Prevention identified Salmonella enterica serotype Newport. The strain is resistant to several antibiotics, most notably azithromycin-a recommended treatment for Salmonella enterica . Before the outbreak, azithromycin-resistance in this germ was exceedingly rare. In fact, it was only first seen in the US in 2016.

Yet in the 2018-2019 outbreak, it reached at least 225 people in 32 states. Of those sickened, at least 60 were hospitalized and two died.

Infectious disease researchers investigate the cases of backdoor infections from the US and soft cheeses from Mexico (mostly queso fresco, which is typically made from unpasteurized milk). Genetic testing suggests that cows in both countries are carrying the germ.

In a report published August 23 by the CDC, the investigators note that just a year earlier, the Food and Drug Administration has recorded a spike in the use of antibiotics called macrolides by cattle farmers. From 2016 to 2017, cattle increase their use of macrolide antibiotics by 41%. Macrolides are a class of antibiotics that includes azithromycin. Because antibiotics within a class could lead to resistance to other drugs in the same class.

Newport strain.

"The use of antibiotics in livestock can cause selection of resistant strains, the reported 41% rise in cattle, "they wrote."

"Avoiding the unnecessary use of antibiotics in cattle, especially those that are important for the treatment of human infections, [1969019] Newport with decreased susceptibility to azithromycin. "

In recent years, around 70% of all medically important antibiotics have been sold in animals.

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