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Diet capsules that swell in the stomach can contribute to weight loss Life and style

Gel capsules that partially fill the stomach before a meal can help people lose weight and maintain weight, said the European Congress on Sunday's Obesity.

The hydrogel capsule only made the news in 2010 when it was called Attiva Now, as Plenity, it has been tested on more than 400 people. It only worked for 59% of people, but doubled their chance of losing 5% to 10% of their body weight.

Diet pills had a pseudo history and only one is approved for NHS use in the UK. Xenical ̵

1; which is not very popular due to its functionality. It prevents fat from being absorbed so that it goes straight through the body and can lead to stomach or intestinal problems.

Plenity, manufactured by the US company Gelesis, is technically more of a medical device than a drug needing such extensive trials. The capsules contain cellulose hydrogel contained in fruits and vegetables and citric acid. Three capsules are taken with two glasses of water 20 minutes before a meal. They absorb water and swell in the stomach.

"What happens is that these small particles are released in your stomach and turn into a gel. This gel takes up about 250 ml of your stomach – about a quarter of its volume, "said Dr. Harry Leider, chief physician of Gelesis.

" This gel – it's like chewed vegetables – mixes with food. This will make you feel fuller when you eat, so you do not eat so much. That's the main mechanism. "

The gel is not absorbed. It goes through the small intestine and then goes to the colon, where it is degraded, the water is absorbed and what is left, exits in the feces.

"Because there is no chemical interaction with the body, it is not absorbed. it is mostly mechanical. It has a really good safety and tolerability profile, "he said. "That's why it's regulated as a device rather than a drug."

"It's recommended that it's an aid in weight loss in conjunction with diet and exercise. We encourage patients to contribute prudently to nutrition, and focus on exercise because we know it will help people to succeed. Nothing is the silver ball. This is a new instrument in our armory. "

The study involved 436 people, half taking the capsules and the other half taking a placebo. All were overweight or moderately obese and tried to lose weight through diet and exercise. The average weight at the beginning was about 100 kg. Patients in the placebo group lost 4.4% of their body weight and those taking the active capsules lost 6.4%. Adjusted for differences such as starting weight, age and gender, Leider said there was a 2% weight loss over placebo.

Obesity experts said the capsules, which could be available in pharmacies from next year, could be useful. 19659002] "I would warn against magic bullets, but for a certain group of consumers who are doing the right things in terms of diet and exercise, this can help keep them on track," said Prof. Jason Halford of the University Liverpool meeting in Glasgow, where the results of the study were presented.

"This could be of great help to millions of people. It is well tolerated and increases satiety, so people eat less. You do not need a surgeon, you just buy it in a box and swallow a pill. It seems to be simple and effective so millions could benefit, "said Dr. Nathalie Farpour-Lambert, president of the European Association for the Study of Obesity.

Prof Helen Stokes-Lampard, chairwoman of the Royal College of GPs "It sounds like an interesting development, and the non-invasive nature of a pill would be attractive to many patients and health professionals," she said. "But we need to be careful when we do this as a new one Miracle medicines look at weight loss because non-medical approaches to a healthy lifestyle should always be explored first, so that as a society we do not become dependent on medical intervention. "

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