IGOR STEVANOVIC / 123rf
One group will spend 1
What if Alzheimer's treatment could come from the supermarket?
Two diets – the Healthy Recommended Diet and The Ketogenic Diet – are being confronted in a Waikato study to see what makes the difference for people with progressive brain disease.
And researchers behind the project are currently looking for people to participate in the study.
"Alzheimer's is the elephant in space in medicine," said neurologist Waikato DHB Matt Phillips.
"Heart disease, stroke, even cancer, they are not rapidly increasing, Alzheimer's doubles every 20 years."
"I have nothing on the horizon that can improve it.  Phillips believes that the diet could help, and is the lead investigator for a 12-week study that examines two eating styles.
A group of participants will eat the healthy diet normally recommended for patients with Alzheimer's will: health diet ", and the Japanese diet.
That means lots of fruits and vegetables, healthy carbohydrates, low-carbohydrates, sugar and fat, and limited dairy products, Phillips said.
The second group will focus on the low carbohydrate, high fat ketogenic diet that mimics fasting.
Phillips said ingredients such as coconut oil and avocado are present, but there will be no starchy vegetables, and berries are the only fruit.
Both diets contain about the same amount of protein and vegetables, Phillips said. 19659005] Currently, more evidence supports the healthy, recommended diet, but studies have also begun to deal with the ketogenic diet.
Since it imitates fasting, it may be that the body is transformed into cell maintenance and repair processes.
"We can not tell if the diet can slow the disease down in this study," Phillips said.
"We need to see if it makes a difference first, but theoretically diet therapy may well be in place." Slow the illness.
"A drug approach is a single goal, symptomatic. Diet approach is multi-target, possibly disease modifying." And one more big thing: patient self-empowerment .You do not have to go to your doctor … get your pills. "
No one knows what causes Alzheimer's, he said," But for some reason, neurons die in certain parts of the brain. "19659005] The two worst affected areas are responsible for remembering personal experiences and facts.
Currently, "a handful of medications" are used to treat, but they mask the symptoms as opposed to curing the disease.
Phillips has previously conducted a similar Parkinson's disease diet study, which found that the ketogenic diet leads to major improvements in symptoms for which the medication does not work well.
The Alzheimer's trial runs for three months and patient improvement is measured in three key areas: knowledge, home function and quality of life.
If you want to participate, you must meet the following criteria: 50 to 80 years old, have mild Alzheimer's disease, live with someone who can be your study partner, and make five visits to Waikato Hospit al.
They receive support 24/7, are reviewed by several doctors and nurses, and receive APO-E4 genetic testing.
The trial is expected to begin in mid-2019 and is supported by the Waikato Medical Research Foundation.
For more information, visit the website or email Matthew Phillips.