قالب وردپرس درنا توس
Home / Health / Everything You Need to Know About Colon Cancer, Health News & Top Stories

Everything You Need to Know About Colon Cancer, Health News & Top Stories



What is it?

Colon cancer begins in the colon (large intestine) or in the rectum (rectum). It is the most common cancer in developed countries today. People living in these countries have the threefold risk of developing this.

In Singapore alone, 9,324 cases of colorectal cancer were diagnosed between 2010 and 2014, with both men and women equally at risk. It is now the most common cancer among men and the second most common cancer among women in Singapore. Although it can occur at any age, it is usually diagnosed among over-50s. If it is detected early, it can be prevented or effectively treated.

Ninety percent of colon cancer cases almost always start with a polyp. However, it may take five to 1

0 years for normal cells in the lining of the colon or rectum to mutate and experience "methylation abnormalities". This is when the cells change and grow without control. If a gene mutates over time, a non-malignant polyp can become cancerous.

Beware of inherited risk

About five to ten percent of all colorectal cancers can be hereditary.

The two most common inherited bowel cancer syndromes are hereditary non-polypous colorectal cancer (HNPCC) and familial adenomatous polyposis (FAP). HNPCC cases account for between three and five percent of the population, while FAP cases are less than one percent.


Polyps can be removed from the colon. PHOTO: iSTOCK

People with the same cancer syndrome as their family members are more at risk and the cancer can develop before the age of 50. For example, those with HNPCC often have at least three family members and two generations with colorectal cancer. FAP patients may have hundreds of polyps in their early teens that can not become cancerous.

A chronic inflammatory bowel disease (Crohn's disease or ulcerative colitis) also increases the risk of colorectal cancer. The risk is higher if inflammation affects the entire colon.

Look at the bright side

Between 2005 and 2014, the survival rate of men and women has risen from 45 percent to 50 percent in all ethnic groups.

Medical advances, especially in the field of personalized medicine, have increased the chances of survival. In addition, genomic profiling helps to tailor treatment to the cancer characteristics and genetic makeup of the individual.

New medications such as cetuximab and panitumumab, which cleverly discourage bowel cancer cells from further growth, have proven to be well-suited Patients with the non-mutated (wild-type) KRAS and N-RAS gene

A form of cancer treatment, an immune therapy that cures the body's immune system against cancer, also provides hope for some colon cancer patients

Cultivate the good

It helps to exercise self-control in your lifestyle and eating habits.

Stop Smoking: Every shot of a cigarette contains more than 60 carcinogenic carcinogens.

Limit alcohol intake: Alcohol can act as an irritant. Damaged cells could try to repair themselves, which could lead to DNA changes in the cells. In the colon and rectum, bacteria can convert alcohol into large quantities of acetaldehyde, a chemical that has been shown to cause cancer in laboratory animals. Men should limit their intake to two alcoholic drinks and women to one alcoholic beverage per day.

Exercise regularly: One hypothesis is that high levels of insulin or insulin-induced growth factors in overweight people can promote colorectal cancer development. Maintain a lower body mass index (BMI) to reduce the risk of colorectal cancer.

Watch the diet: Avoid excessive consumption of red and processed meat foods with animal fats such as ham, bacon, sausages and local delicacies, Bak Kwa are some examples. It is recommended to limit intake to 500 grams of cooked meat per week with large portions of fresh fruits and vegetables per meal.


Based on the HPB guidelines, a colonoscopy should be done every five to ten years PHOTO: PARKWAY CANCER CENTER

Go to a colonoscopy

Many people is not yet clear how a colonoscopy can prevent colon cancer.

Because It Takes Five to Ten Years To make a polyp cancerous, colonoscopy – a relatively painless and uncomplicated procedure – can make a big difference. Based on the guidelines of the Health Promotion Board (HPB), a colonoscopy should be performed every 10 years if the results of the initial colonoscopy show no anomalies and there is no increased risk of colorectal cancer

High-risk individuals with family members who should have colon cancer earlier After discussion with the appropriate medical professionals for a colonoscopy.


Source link