Frank Field has told his constituents that he is leaving the Labor whip because of the party's "dreadful culture."
Veteran MP, who represents Birkenhead for nearly 40 years, said under Jeremy Corbyn's leadership that it is now "a party to anti-Semitism that is more than tolerated."
He wrote in the Liverpool Echo that he expressed "considerable sorrow "left the party group in parliament.
A Labor Party spokesman thanked Field for his service to Labor.
Mr. Field was among the MEPs to nominate Jeremy Corbyn for the leader in 2015, but said he would do so to ensure a "broad debate" on the leadership and never expected him to win.
"My desire to see a broader debate in the Labor Party could not have gone on," he wrote.
It is expected that he will meet Labor Chief Whipper Nick Brown on Friday to discuss his options after saying that he wants to serve as an independent MP while remaining a member of the party. However, sources of work have said that this will not be possible.
Under the parliamentary Labor Party, which governs deputies, anyone who takes such action usually receives a letter requesting that they retake the whip within two weeks – or resist expulsion.
Mr. Field has left the party's faction by letter to Mr. Brown on Thursday that the leadership will "become a force for anti-Semitism in British politics".
The parliamentarian who joined his constituency party last month because of his pro-Brexit Attitude lost a vote of confidence, also accused a "culture of intolerance, vulgarity and intimidation" in local parties.
Jeremy Corbyn has apologized for the injuries caused by anti-Semitism in the party and promised to eradicate it.
A lab source claimed that "Frank has sought an apology for some time to withdraw."
In the article for his local newspaper, M Field said, the reason why he was one of the 36 MPs to nominate Mr. Corbyn for the party leadership was "to include the hard left as these views are a legitimate place in the Have Labor thinking ".
But he added: "After Jeremy's election as leader and the growth of party membership, which under normal circumstances would be welcome, we have become a party that shows intolerance, abomination and intimidation at all too many levels."  Complaints "Silence"
Mr. Field said his constituency party was characterized by "brash brawl and obvious bullying" with "racist, age-related and sexist intolerance".
He also said that his complaints to the National Party had been made "with silence" and that such behavior "is a cause for disgrace and unacceptable" to him.
Mr Feld, the former Minister of Welfare Reform, lost a vote of confidence in his constituency party after voting with the government over Brexit's plans.
On Thursday, he denied that he "jumped before he was pushed" and used the article to further convict some local members.
He reiterated that he would remain a member of Labor, but added: "I can not give legitimacy to the most appalling culture that now dominates national and local Labor Party institutions by the Labor whip."
Mr. Field completes the article by making two "major changes" calls.  "Firstly, the current excuses for the overtly racist tolerance of anti-Semitism must cease and we must regain our position as the leading force against racism in this country," he wrote.
"Secondly, the party must acknowledge the culture of intolerance, malice and intimidation that has allowed it to grow unchecked and drive away local members whose behavior in public is simply disgraceful."
Praise and criticism
A series of Mr. Field's Labor colleagues praised him and expressed concern over their party.
Labor Party Vice-President Tom Watson described the resignation as a "serious loss to the party" and a "big wake-up call".
MP Mary Creagh said that the fact that Mr. Field's local party wanted to veto him "speaks volumes about the state of our party."
And colleague MP Siobhain McDonagh has called Frank Field a "Labor Warrior" and told BBC's Newsnight, "Do not we want loners in our politicians and our MPs who are ready to stand up and say it as it is?"
He was also applauded by some Conservative MPs, with Interior Minister Sajid Javid chirping that he was "a man of integrity and principle."
But Corbyn-supporting Labor members have criticized the decision of Mr. Field.
MP Chris Williamson condemned his colleague's comments as "grotesque denunciations that have no basis in reality."
He told Newsnight: "The party has taken the issue of anti-Semitism very seriously, much more seriously than anyone else
" It is so sad to see someone like Frank Field destroy the anti-racist record of the Labor Party. " And Labor's Shadow Justice Minister Richard Burgon said Mr. Field should face a by-election.
Labor A Series on the Extent of Anti-Semitism Joke (19659007) An investigation by Shami Chakrabarti in 2016 came to the conclusion that the Labor Party was not from An tisemitism was flooded, but "occasionally toxic atmosphere" prevailed.
There has recently been a focus on a new code of conduct adopted by the Party on anti-Semitism, with critics fearing that this will not go as far as the International Holocaust Remembrance Alliance guidelines
Corbyn once again apologized for it Anti-Semitism in his party suffered violations of the Jewish people and acknowledged that Labor had dealt too slowly with disciplinary cases.
Mr. Corbyn also emphasized that people who advocate anti-Semitic views have "no place in the party." Labor Party "and said that people who use" anti-Semitic poison "are not his backers, nor are they speaking for him or the party.