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Frequent daily medication increases the risk of serious internal bleeding, doctors warn



Those who take aspirin every day should be aware of the associated risks, the researchers behind a new study say: while reducing the risk of a heart attack or stroke, the risk of serious internal bleeding increases.

This study is about adults without existing heart disease, and the scientists say the potential dangers outweigh the potential benefits. So think twice about whether you should drink one aspirin a day in the future. 19659003] The new research is a metastatic study of past clinical trials that looks at trends and patterns in more than 164,000 individuals, and challenges traditional wisdom that daily aspirins are a safe way to reduce the risk of heart disease. especially for the elderly persons.

"This study shows that there is insufficient evidence to recommend the routine use of aspirin to prevent heart attacks, strokes and cardiovascular deaths in people without cardiovascular disease," says one of the researchers, King Sean Zheng. # 39; s college in London UK.

"There was more uncertainty as to what to do in patients at risk for cardiovascular disease and in patients with diabetes." This study shows that while cardiovascular events in these patients may be reduced, they do There is an increased risk of major bleeding events. "

Even before this study appeared, the experts said that patients should only regularly take low aspirin doses a doctor's advice ̵

1; there are many health factors that are considered with the blood-thinning drug even if we know that it can be a very effective drug.

Now the picture is a little clearer Among those who participated in the meta-study, those who took aspirin daily had a 0.38 percent lower absolute risk of heart attack, stroke, or cardiovascular death events.

At the same time, a daily habit of aspirin associated with 0.47 percent was higher absolute risk for severe internal bleeding. This underlines the importance of not doing so until you talk to your doctor about it.

Kevin McConway of the Open University in the UK, in which he was not involved The investigation told Rich Haridy at New Atlas, how this would convert into real numbers.

For a daily aspirin, 57 instead of 61 people per 10,000 should have a heart attack or stroke; At the same time, an average of 23 instead of 16 people per 10,000 people suffer from heavy bleeding.

"This raises the serious question of whether people who previously had no heart attack or stroke should take aspirin to reduce future cardiovascular events," Zheng told Lisa Rapaport in Reuters.

The mean median age of all study participants was 62 (ranging from 53 to 74). About half of them were persecuted for at least five years.

One of the limitations of the research is that the different studies they examined covered different daily doses of aspirin – from 50 mg to 500 mg. Doctors usually do not prescribe more than 100 mg a day. However, it is worthwhile for patients and physicians who weigh the pros and cons of using aspirin as a preventative measure and may consider alternative options (such as blood control) to pressure or quit smoking instead.

In an accompanying editorial to the study, Michael Gaziano of Brigham and Women's Hospital in Boston, who was not involved in the main research, said aspirin was still "an important drug" for the prevention of cardiovascular disease. Illness is a question – as long as we use it wisely.

"The use of aspirin requires discussion between the patient and their physician, bearing in mind that all small potential cardiovascular benefits are balanced against the actual risk of major bleeding," says Zheng. 19659003] The research was published in the Journal of the American Medical Association .


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