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Further evidence screening mammograms are not required for many older women



By Lisa Rapaport

(Reuters Health) – Screening mammograms do not benefit women over the age of 75 years with chronic health conditions such as heart disease or diabetes new study suggests.

Researchers studied data on 222,088 women who had at least one screening mammogram between 1999 and 2010, between the ages of 66 and 94 years. The researchers tracked most women for nine years or more.

During the study, 7 583 women (approximately 3%) were diagnosed with invasive breast cancer, and 1,742 women (less than 1%) were diagnosed with pre-invasive malignancies known as ductal malignancies. Carcinoma in situ (DCIS). While 471 women died of breast cancer during the study, 42,229 died from other causes.

This means that women die 90 times more likely to have causes other than breast cancer, researchers report in the Journal of the National Cancer Institute.

] "Chronic diseases increase the risk of dying from non-breast cancer while not compromising the risk of breast cancer or death from breast cancer," said Dejana Braithwaite, lead author of the study and researcher at Lombardi Comprehensive Cancer Center Georgetown University in Washington, DC

"This is a big deal, as younger women may have a more legitimate reason to undergo breast cancer mammography because their risk of dying from other causes is relatively low is not the case in older women, especially women with one or more chronic conditions, "Braithwaite said by e-mail.

Women aged 75 to 84 died 1

23 times more frequently from causes other than Br Ost cancer; This estimate was even higher for women 85 and older.

The 10-year risk of dying from breast cancer was low and did not vary by age. It remained roughly the same from age 66 to age 94, accounting for only 0.2% -0.3% of all deaths in the study.

On the other hand, for other reasons, the risk of death increased with age and increased with every other chronic condition of a woman's problem.

The goal of mammography screening is to detect tumors before they are felt during a physical breast exam, and to get cancer faster if treatment is easier. Ideally, this should mean that fewer women are diagnosed as tumors grow larger, grow rapidly, and are more difficult to attack.

However, some studies suggest that too early or too frequent screening can also catch more small, slow-growing tumors where death is unlikely – without the diagnosis restrict advanced cancer cases. The consequences of over-screening may include unnecessary invasive sequelae and cancer therapies for tumors that never made women sick or death.

The US Preventive Services Task Force notes that there is not enough evidence that could be recommended for or against the screening of women over 75 years of age. Many breast cancer programs in Europe stop screening women between 69 and 74 years old.

Despite these recommendations, many women in the US still receive screening mammograms in the 1980s and 1990s, according to the study team.

One limitation The analysis included only women who continued to receive mammograms as they became older, and it is possible that all women in the population, including those who did not receive mammograms, achieved different outcomes.

"Our study included a large number of older women who are unlikely to benefit from mammography," said Braithwaite. "Women aged 75 and over are unlikely to benefit from continued mammography, but these findings underscore the need for more personalized screening strategies rather than making comprehensive recommendations."

SOURCE: https://bit.ly/ 2kcRguy Journal of the National Cancer Institute, online, September 6, 2019.


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