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Home / Health / Genetic researchers reverse wrinkles, hair loss in mice, USA News & Top Stories

Genetic researchers reverse wrinkles, hair loss in mice, USA News & Top Stories



WASHINGTON (XINHUA) – A research team from the United States has identified a gene in mice that reverses wrinkles and hair loss and can be applied to humans in the future, local media reported.

"Skin and hair crumple loss are hallmarks of aging, what if they could be reversed?" University of Alabama in Birmingham (UAB) noted a breakthrough in research.

In the study, mice received an antibiotic that changed their gene.

The antibiotic induced a mutation and the mice developed wrinkled skin and suffered extensive hair loss within a few weeks.

The mutation was caused by the mitochondria, small organelles in the cell that function like the digestive system of the cell become dysfunctional (1

9659002). Mitochondrial function was restored; the mice returned to smoother skin and a thick coat, which was replaced by a healthy mouse of the same age was indistinguishable.

"To our knowledge, this observation is unprecedented," said Keshav Singh, professor of genetics at the UAB School of Medicine

Singh said the mouse model should provide an opportunity for the development of preventive and therapeutic drug development strategies to mitochondrial functions for to treat those treated t from age-associated and other diseases.

In humans, a decrease in mitochondrial functions is observed during aging, and mitochondrial dysfunction can lead to age-related diseases. Depletion of DNA in mitochondria is also associated with human mitochondrial diseases, cardiovascular disease, diabetes, age-related neurological disorders, and cancer.


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