New research has shown that poliovirus can be life-prolonging in patients diagnosed with glioblastoma, the deadliest brain tumor.
Dr. Steven Toms, neurosurgeon at Rhode Island Hospital and director of the brain tumor program, explains why it is so deadly, with an average life expectancy of two years.
"No matter what I do, there is always a part of the tumor left behind." Although MRI looks perfect, there are many hundreds of thousands, if not millions, of tumor cells, "says Dr. Toms.
" Glioblastomas very difficult to treat, "says Dr. Alexander Mohler, a neuro (19659005) He says chemo and radiation helped, but new research from Duke University suggests that the poliovirus in combination with the common cold virus could prolong life in some patients
"It is you who are given a so-called convection-enhanced administration, so they basically put a tube into the tumor and administer the drug," said Mohler.
"Here we are trying to hijack the body's immune system "We all got our polio virus vaccines," Toms said.
Toms says everyone was exposed to the common cold virus.
"What the Duke program is trying to do now is kidnapping the body's ability to recognize some of the proteins from the Pole The virus and rhino virus set off a fire under our immune system and say: Hey guys, come on, let's attack the glioblastoma cells where these viruses are expressed after they are brought to the brain, "said Tom . This was a small study of 61 patients. One in five had prolonged survival, but it's just a tool, Toms says.
There are other immunotherapies, and something called tumor therapy field therapy. The patient wears a cap with four electrode sets.
These electrodes disrupt cancer cells when they try to divide and spread.
"Personally, I have a few patients who are now over 8 years old. This treatment has no signs of illness," Toms said.
To learn more about glioblastoma, click here.