Aspirin is still one of the most commonly used drugs in the world, although it is no longer recommended as a preventative by many health authorities.
There is no evidence that low-dose aspirin – less than 325 milligrams a day – should be taken by most adults with good cardiovascular health. This emerges from a new review of existing research results published on Wednesday in the British Journal of Clinical Pharmacology.
The review, which focused on the risks and benefits of low-dose daily aspirin, found that the risk of a serious bleeding event due to the blood-thinning effects of the drug outweighed the benefits.
This most recent analysis, which examined 67 studies, found that the use of low-dose aspirin in people without cardiovascular disease was associated with a 1
However, it was also associated with a 47% higher risk of gastrointestinal bleeding and a 34% higher risk of skull bleeding.
“Our article confirms that there is no evidence of aspirin in primary prevention, that is, in healthy people,” said the study’s authors, Dr. Lee Smith, Physical Activity and Public Health Reader at Anglia Ruskin University in the UK, and Dr. Nicola Veronese. A geriatrician at the University of Palermo in Italy said in an email.
“The takeaway in our article is that low-dose aspirin is (only) good if you already have cardiovascular disease.”
However, according to experts, it is important to speak to your own doctor before making changes to the medications you take.
“Low-dose aspirin is one of the most commonly used drugs in the world. In addition, our umbrella report suggests that the weight of risks, particularly bleeding, should not be considered secondary,” said Smith and Veronese.
Given the variety of different interventions now available to prevent cardiovascular diseases such as statins, blood pressure medication, and smoking cessation and weight loss, the results of the research questioned the use of aspirin as a preventative.