<img src =" https://media.npr.org/assets/img/2019/03/19/weed-bud_sq- 0a51e80d3bb5e5893162e2d6aac0164eddb09698-s100-c15.jpg "data-original =" https://media.npr.org/assets/img/2019/03/19/weed-bud_sq-0a51e80d3bb5e5893162e2d6aac0164eddb09698-s100.jpg "class =" img lazyOnLoad "alt = "Daily marijuana use and highly effective weed related to psychosis  The potential health risks of highly effective weeds may not be clear to humans." The negative effects of cannabis were mainly limited to THC, "says Gruber Risk exists for a negative result . "
" In general, people think, "Oh, I do not have to worry about marijuana. It's a safe drug, "says Nora Volkow, director of the National Institute for Drug Abuse. The idea that this is a completely safe drug is wrong when you look at the consequences of this very high level of 9THC. "
Pot's Paradoxical Effects
THC can have adverse effects on our body in high and low doses, says Volkow. For example, take anxiety.
" If someone marijuana in low doses takes. [THC] Relaxation and relaxation feelings reduce your anxiety, "she says, but high concentrations can lead to panic attacks, and if someone drinks enough THC," you become psychotic and paranoid. Weeds can have a similar paradoxical effect on the vasculature Volkow says, "If you take low-THC, it increases your blood flow, but high levels [THC] can cause massive vasoconstriction and reduce flow through the vessels ,
In low concentrations, THC can be used to treat nausea in cancer patients undergoing chemotherapy, but Volkow says that "patients with high levels of THC use are chronic with a syndrome in the emergency room, where they could not stop vomiting, and with severe abdominal pain. "
It is a disease called cannabinoid hyperemesis syndrome.
typical patients use [inhales] about 10 times a day … and they get really difficult to treat nausea and vomiting, "says Andrew Monte, associate professor of emergency medicine and medical toxicology at the University of Colorado Medical School. "Some people have died of this … syndrome, so it's worrying."
Scientists do not know exactly how high THC levels can trigger the syndrome, but the only known treatment is the cessation of cannabis use.
While the number of people who have had the syndrome is low, Monte and his colleagues have documented an increase in emergency department cases in Colorado since marijuana was legalized there five years ago. A study by Monte and his team found that cases of cyclic vomiting in his ER accounted for about 18% of inhaled cannabis cases.
They also found that the total number of cannabis-related emergencies has risen across the state. And Monte says his emergency room "saw a tripling in the number of visits to the emergency room." This does not mean that we are overwhelmed by these visits due to cannabis, but that more patients are present overall. "
Most people emerge in his ER because they are" intoxicated "and have too much potion, either directly or mixed with other drugs, Monte says, the majority of these cases being due to inhaled cannabis, although edible drinks with
"We see an increase in psychosis and hallucinations, as well as anxiety and even depression and suicide," says Monte.
He believes that the increased potency of marijuana plays a role in all these cases. "Whenever you receive a higher dose of any of these types of medicines, the patient is at greater risk for adverse drug reactions. When the concentration is so much higher, it's much easier to exceed the low peak. "They're looking for."
Not everyone is equally at risk, adds Monte. "Many, many people consume cannabis safely," he says. "The vast majority do not end up in our ER."
Different Risks for Consumers
Some people are more vulnerable to the possible negative effects of high THC cannabis than others.
Adolescents and young adults who spend their leisure time are particularly vulnerable because their brains are still developing and generally sensitive to drugs, Gruber says of the MIND program. In a recent review of existing studies, she found that adolescent marijuana use affects cognition – especially memory and executive functions that determine mental flexibility and ability to change our behavior. "It's very important that people understand that they may not get the expected response," Gruber notes.
Studies on the medical benefits of pots usually involve very low THC doses, says Monte, adding that these doses are "much lower than what people are currently receiving in a pharmacy".
David Dooks, a The 51-year-old from the Boston area turned to marijuana following an ankle operation last year. "I thought that medical marijuana might be a good alternative to opioids for pain therapy," he says.
Based on the advice in a pharmacy, David began to use one weed with 56.5% THC, and said that this only enhanced the effect of nerve pain. "After experimenting with a few other strains, one of his low (0.9%) THCs was effective, which alleviated his nerve pain.
& # 39; start low, go slow & # 39
Regardless of whether people spend their leisure or medical lives, patients should train as well as possible and be careful with their use, says Monte.
Avoiding higher-level products "THC content and rare use can also help reduce the risk," adds Volkow, adding, "Those who have had bad experiences, be it psychic or biological, should stay away from this drug," she notes.
Ask "You need to know what's in your grass," says Gruber, "whether it's a conventional flower you smoke or vapour, an edible flower, or a tincture 'It's very important to know what's in it.'
And the old adage, "slowly starting," is a good rule of thumb, she adds. "You can always add, but you can never take it away. Once it's in, it's in."