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Hopes for eradication of cervical cancer



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The success of the HPV vaccine suggests that one day cervical cancer will be eradicated, say scientists who have carried out a comprehensive review of the evidence.

The vaccine against the human papillomavirus, which causes most cervical cancers, started more than a decade ago.

A Lancet survey of 65 studies in 60 million people showed a decrease in HPV cases and growth against cancer.

Over decades This should be reflected in a significant decline and possible eradication of the cancer they mention.

Jo's Cervical Cancer Trust said the data should boost confidence in the trick.


What is Human Papillomavirus (HPV)? [1
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  • HPV is the name of a common group of viruses. There are more than 100 HPV types.
  • Many women will be infected with HPV during their lifetime without any adverse effects.
  • Most cervical cancers are caused by infection with a high-risk HPV.
  • Other causes disorders, including genital warts and cancers of the head and neck
  • The vaccine, which is administered to girls aged 12 and 13 years since 2008, protects against four HPV types – 16 and 18, with more than 70% of cervix cancers are related. and six and eleven, which cause about 90% of genital warts.

Source: NHS Decisions


Each year, there are 3,200 cases of cervical cancer and 850 deaths from the disease.

Evidence

The review included studies in 14 high-income countries, including the United Kingdom. They examined HPV rates as well as cases of genital warts and precancerous cells in the cervix called CIN.

The following were found when the rates were compared before vaccination and eight years later:

  • HPV-16 and HPV-18 cases decreased by 83% in girls aged 15 to 19 – 66 % in women aged 20-24 years
  • Genital warts fell 67% among girls between the ages of 15 and 19 – 54% among women aged 20-24
  • Growth against cancer declined 51%% in girls 15-19 – 31% in women 20-24

It also showed that people who were not vaccinated benefited. The cases of genital warts in men aged 15 to 19 decreased significantly by almost 50% and also in women over 30 years.

In countries where a wider age group was vaccinated and where coverage was higher.

Public Health The Principal Scientist of England, dr. David Mesher, said: "We are seeing a reduction in HPV and cervical cancers, so there is every indication of cervical cancer reduction."

Prof. Marc Brisson from Laval University, Canada, who led the review, said, "Over the next 10 years, we will see a reduction in women ages 20 to 30 years."

He said that elimination of cervical cancer – defined as less than four cases per 100,000 – could be possible if that suffices. A high vaccination coverage can be achieved and maintained. "

Jo's Cervical Cancer Trust said the results" clearly showed "the effects of HPV vaccination.

" This study supports growing evidence to counteract those who do not believe this vaccine works, whi ch is now extremely encouraging, "said CEO Robert Music.

" We sincerely hope that this will increase public confidence in the HPV vaccine, so that more lives can be saved and we are approaching a world in which cervical cancer matters plays the past. "


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