Salamanders are known for their ability to regenerate, such as regrowth of whole limbs. We can not go through this biological trick, but new research proves a hitherto unknown human regenerative capacity, an ability that depends on our evolutionary past.
Our body has preserved the ability to repair injured or overworked cartilage in our joints, it says new research published today in Science Advances. Remarkably, the mechanics of this healing process are virtually the same as with amphibians and other animals to regenerate lost limbs.
"We call it our inner salamander ability."
The Scientists Those who have identified this previously unknown human ability are confident that their findings will lead to powerful new therapies for treating common joint disease and injury, including osteoarthritis , could lead. More radically, this healing mechanism "could be used to improve repair of the joints and provide a basis for the regeneration of the human limbs," the authors wrote in the article.
Some animals, such as axolotls zebrafish and bichir fish, are able to regenerate various body parts. The Axolotl is special in that it can regrow its limbs, organs and even parts of its brain. The fact that people can not grow whole limbs is hardly new, but scientists previously thought that we too are unable to repair damaged and deteriorated cartilage in our joints ourselves. To better understand this obvious human limitation, researchers from Duke University School of Medicine and Lund University sought to determine how long proteins actually remain in the cartilage.
"This led us to believe that the cartilage proteins of the knee were generally younger than those of the hip of people of similar age," wrote Virginia Kraus, professor of medicine at DUSM and co-author of the new study , at Gizmodo. "By younger, we mean that they have accumulated fewer modifications of their structure, which naturally accompanied aging over time. As a result, we wanted to examine ankle cartilage and, in fact, found that the same proteins were even younger. A "salamander-like" ability to regenerate damaged body parts. Study results ” data-poster-src=”” data-anim-src=”” data-cropped=”false” class=”dv4r5q-1 hEuYft”/>