The strike, which is believed to be the first in Iraq for several decades, was likely targeted against militia groups that are closely related to Iran. Voters are conducting a retaliatory attack.
In the US, around 5,200 soldiers are stationed in Iraq to help Iraqi forces fight the remains of the IS.
The US officially refused to say whether Israel was involved, but refused any responsibility for the strike and called for respect for Iraq's sovereignty.
Several other Iranian-backed military units in Iraq have also been shaken by a series of explosions, but at this point in time, the US believes that Israel is responsible for only one of these explosions. that several other scenarios could have caused the other explosions, including bad practices regarding the storage of ammunition and explosives.
The Pentagon has denied any involvement in the explosions that have taken place in facilities and military camps associated with a group of militias known as the People's Mobilizing Forces of Iraq, many of whom are supported by Iran.
Pentagon spokesman Cmdr asked about the possibility of Israel being behind one of the strikes. Sean Robertson said: "We support the sovereignty of Iraq and have repeatedly spoken out against possible actions by neighbors that could lead to violence in Iraq, and Iraqis have the right to control their own internal security and protect their democracy." An Iraqi diplomat told CNN that the Israeli strikes and US knowledge about them are a potential game changer in US Iraq, and asked the Iraqi foreign minister to discuss the incident
However, a US State Department official denied that the American diplomat had been called and said that the meeting had been planned in advance and they had met "to discuss a variety of topics".
Following the explosions, the Iraqi government has issued new restrictions on the use of Iraqi airspace. These provisions affect the US-led military coalition that is fighting ISIS.
Israel has publicly admitted airstrikes against Iranian targets in Syria, but has yet to admit it is involved in air strikes in Iraq.
Israeli Prime Minister Benjamin Netanyahu has refused to confirm ̵
Asked in an interview on Israeli channel Channel 9 on Thursday whether Israel is conducting operations in Iraq, Netanyahu, who also acts as the country's defense minister, said, "We are acting in many areas against a country trying to destroy us. Of course, I gave the security forces a free hand and ordered them to do what was necessary to thwart Iran's plans. "  When describing the threat, the Israeli leader accused Iran of "building bases against us throughout Iran, Lebanon, Syria, Iraq and Yemen".
"I do not give Iran immunity anywhere." N etanyahu added.
The Pentagon also warned Iran against "using Iraqi territory to threaten other countries in the region," Robertson said in a statement. "Iran must not use Iraqi territory to threaten other countries in the region, and Iran's destabilizing activities undermine Iraq's security and increase the risk of regional conflict."
Andrew Carey and Mike Schwartz of CNN contributed to this report.