Singleton, 51, was in the facility on Wednesday when he had the stroke, the family said in a brief statement that contained no details.
Hollywood celebrities used social media to send congratulations to Singleton.
Actor Omar Epps, who starred in the Singleton-directed film "Higher Learning," tweeted, "Director John Singleton wanted a speedy recovery from his stroke, and an opportunity for us to marvel at this human physiology works at all."  Rapper Snoop Dogg posted a picture of himself and Singleton on Instagram and said, "Pray 4, my brother."
Film director Guillermo del Toro, a two-time Oscar winner, wrote on Twitter: "Get Well, John Singleton! Such a generous spirit. "
Singleton was nominated for best director and best screenplay for "Boys n the Hood," released in 1
Film critic Roger Ebert praised the film as a "human drama of rare power."
Singleton is a director who brings together two qualities that are not always found in the same movie: He has a theme and he has a style, "wrote Ebert." The film is not only important but also a joy too because his camera is so confident and so he wins natural appearances by his actors. "
Singleton was the first African American to be nominated for Best Director.
His recent work includes the FX show" Snowfall " Singleton is one of the creators and executive producers of the show, with Singleton staging three episodes, according to the Internet Movie Database.