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Large people have a higher risk of cancer, says study



Large people are at higher risk for cancer because they have more cells in their bodies, new research suggests.

A person's risk of cancer increases by 10% for every 10 centimeters (4 inches) they have exceeded the average height, the study said, because they have more cells that could mutate and cause cancer.

Average height was defined in the study as 162 cm (5 feet, 4 inches) for women and 175 cm (5 feet, 9 inches)

The results are consistent with previous studies, which also involved an increased risk Including Blood Clots, Heart Problems and Diabetes

Leonard Nunney, professor of biology at the University of California Riverside, analyzed earlier data on people who had cancer ̵

1; each of them they included more than 10,000 cases for men and women – and compared the numbers to expected rates based on their height. [19659002] He tested the hypothesis that this was due to the number of cells against alternatives, such as possible hormonal differences in larger humans, which could lead to an increased cell division rate.

A link was found between a person's total cell The study also found that the increase in risk for women is greater, with larger women suffering 12% more cancer and larger men with cancer getting 9% more likely. These results were in line with Nunney's predicted rates, which used 13% for women and 11% for men.

Colon, kidney and lymphoma were among the cancers for which the correlation was strongest.

"We know there is a long-standing relationship between cancer risk and height – the greater a person is, the higher the risk of cancer," said Georgina Hill of Cancer Research UK to CNN.

"What we have not been [1965-510] surely is the reason – whether that's simply because a larger human has more cells in his body or if there is an indirect connection, such as nutrition and childhood concerns, "added Hill, who was not involved in the study.

She said that the study provides good evidence for the "direct effect" theory that the total number of cells actually causes the compound.

"The methodology is good – it took data from large studies, which is important, and they look You have found that the risk of developing cancer is low compared to the effects the lifestyle can have

"It was only a slightly higher risk and these are more important actions that people can take to make positive changes [stop smoking] and maintain a healthy weight [such as]," she said.

Two of the cancers tested for thyroid cancer and melanoma were more susceptible to an increase in risk than expected, and Nunney suggested in the study that other factors could play a role in these cases, such as geography.

There are no obvious reasons for these exceptions, although the author speculates that cell turnover rates might come into play for melanoma, "said Dorothy C. Bennett, director of the Molecular and Clinical S Ciences Research Institute in London to CNN . Bennett, who was not involved in the study, explained that pigment cells, the source of melanoma, divide and are replaced somewhat faster in larger humans.

"But at the moment I can not imagine why this [faster division] should be so, but also no other clear reason for the higher correlation with altitude," Bennett said.


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