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Home / Health / Mice that have received experimental gene therapy will not get fat, regardless of calorie intake / boing

Mice that have received experimental gene therapy will not get fat, regardless of calorie intake / boing



Researchers at Flinders University proposed a gene known as RCAN1 in mice, suggesting that this would increase the "non-shuddering thermogenesis" that "consumes calories as heat rather than storing them as fat" – the mice were given a high level Calorie diet and did not increase.

In particular, the modified mice did not deposit fat in their midst – a phenomenon associated with many health risks including heart problems – and their dormant muscles burned more calories.

I wrote this into my 2009 maker-maker and described a generation of formerly obese people who were initially looking forward to eating huge meals and then realized that they were in danger of going broke and for all To pay the calories they needed to survive.

The authors of the study point out that RCAN1 has a role and time to prevent calorie burning. Back when food was scarce and calories were not readily available. In the modern world of "high calorie abundance," however, too much fat is stored and real health problems occur. The researchers suggest that "these adaptive pathways of energy consumption [such as RCAN1] can now contribute to the growing epidemic of obesity."

"We looked at different diets with different time periods from eight weeks to six months," said Damien, "and in all cases we have seen health improvements without the RCAN1 gene.

"Mice with a high-fat diet who lack this gene have not gained weight."

A new drug could eat everything without gaining weight [Gavin Butler/Vice]

Calcineurin 1 regulator helps to coordinate total body metabolism and thermogenesis [David Rotter, Heshan Peiris, D Bennett Grinsfelder, Alyce M Martin, Jana Burchfield, Valentina Parra, Christi Hull, Cyndi R Morales, Claire F Jessup, Dusan Matusica, Brian W Parks, Aldons J Lusis, Ngoc Uyen Nhi Nguyen, Misook Oh, Israel Iyoke, Tanvi Jakkampudi, D Randy McMillan, Hesham A Sadek, Matthew J Watt, Rana K Gupta, Melanie A Pritchard Damien J Keating and Beverly A Rothermel/Embo Reports] (Sci-Hub Mirror)

A gene that allows you to eat as much as you like promises obesity [Flinders University/Science Daily]

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Cory Doctorow

I write books. My latest ones are: a YA graphic novel called In Real Life (with Jen Wang); a textbook on art and the Internet titled "Information does not want to be free": Laws for the Internet Age (with introductions by Neil Gaiman and Amanda Palmer) and a YA sci-fi novel entitled "Homeland" (the successor of Little Brother). I speak everywhere and I twitter and also stagger.

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