Scientists have completed the first placebo-controlled study of the effects of the hallucinogen DMT on dormant brain activity, according to a new study.
Dimethyltryptamine is a psychedelic drug known as Ayahuasca. Previous research has examined ayahuasca, but there are not many examples of controlled laboratory experiments with the DMT molecule itself. These new results show how the molecule interacts with the brain and produces a signature of brainwaves that closely resembles a waking dream ,
"These are interesting rhythms that we also find when we dream or during another sleep phase," said Christopher Timmermann, the first author of the study from Imperial College in London, to Gizmodo. "There is an interesting similarity that could point to a common mechanism that these states could have."
The team tested seven men and six women, all of whom had taken a hallucinogen in the past. They connected each volunteer to electroencephalogram (EEG) electrodes for measuring brain waves. Each participant received an intravenous injection of either DMT or a placebo, and then assessed how intense his trip was for 20 meters in minutes after receiving the dose [scientists] data during decreases. A participant's EEG data were not taken into account as they moved too much during the experiment.
Collections of brain cells produce oscillating signals and generate regular activity waves in several frequency bands, including: in order of frequency from low to high: delta, theta, alpha, beta, low gamma, and high Gamma. These frequencies are linked to different functions, and it is determined exactly how they should be interpreted. Such a frequency, the alpha frequency, is more common with the eyes closed and less often with the eyes open. The subjects receiving DMT showed significantly less alpha and beta activity, but generally more diverse types of signals than those given the placebo injection. This was the result of the study published in Scientific Reports .
that DMT users experienced brainwave patterns as if they were in a waking dream, [Timmermann] said . This is consistent with an earlier non-placebo controlled study on smoked DMT, a study on ayahuasca that was consumed as tea and research on other psychedelics reports Ars Technica.
Understanding the effects of psychedelics is important because it can help us learn the basics of neuroscience and brain function, Timmermann said. These medications can cause states of consciousness other than being awake or dreaming that are not well understood.
In terms of applications, scientists are already exploring the potential medical applications of DMT. A recent placebo-controlled study in humans found that ayahuasca had antidepressant effects and another study found similar mood-enhancing effects when rats were administered microdoses of DMT .
More work must be done This is to more closely examine some of the wave patterns observed by the researchers and determine if they have any more meaning. Scientists will continue to explore these new areas of consciousness as these conditions affect our well-being. The article states, "By observing what is lost and gained when the consciousness passes in extreme fashion, psychedelic neuroscience promises to enrich and at the same time enhance our knowledge and appreciation of mind-brain relationships in various contexts inspiring immeasurable applications. "[1