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New Mexico researchers develop vaccine that could prevent Alzheimer's





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UNM's Potential Alzheimer's Vaccine





ALBUQUERQUE, New Mexico – Researchers at the University of New Mexico have developed a vaccine that can prevent Alzheimer's disease, and it's only a matter of time before they pass it to humans test.

Kiran Bhaskar has been passionately studying Alzheimer's disease for the past decade. As associate professor for the Department of Health and Science of the UNM, he said the search for a cure started with an idea in 2013.

"I would say it took about five years for the idea to come into being and fully implemented a working vaccine," he says.

Bhaskar and his team began testing the vaccine on mice.

"We used a group of mice with Alzheimer's disease and injected them through a series of injections," he says Nicole Maphis.

Doctoral student Nicole Maphis says the vaccine was developed to target a specific protein commonly found in the brain of Alzheimer's disease patients.

"As you have seen, we decided on a particular Tau region" We wanted to make a vaccine against it, "Maphis says happily.

" These antibodies seem to have cleared the pathological tau. "Pathological dew is one of the components of this clutter that we find in the brain of patients with Alzheimer's disease, "she says.

The mice were then subjected to a series of labyrinthine tests. The mice receiving the vaccine performed much better than the mice that did not receive the vaccine.

Nevertheless, Maphis and Bhaskar say that this is not yet a complete success. Being able to deliver the vaccine to humans will not only take a few years but can also cost up to a billion dollars.

"We need to make sure we have a clinical version of the vaccine so we can test it for humans," says Bhaskar.

To test just a small group, the Ministry of Health would cost $ 2 million. Currently, Maphis and Bhaskar are seeking partnerships to achieve their goal of a clinical-grade vaccine.

Once they have developed a vaccine that is safe for humans, they must submit it to the FDA for approval. That could take another five years.


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