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New national strategy to increase participation in clinical Alzheimer's studies




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With the disease developing in the United States every 65 seconds and about 5.7 million people already living with it, you might think it would be easy to volunteer For Alzheimer's Research: Not so, the nation's leaders say about the study of aging, and they do something about it.

This is November 35, 1945, which has passed since President Ronald Reagan named him Alzheimer's Awareness Month. At that time there were less than two million people with the disease. Reagan himself succumbed to the ravages of Alzheimer's on June 5, 2004.

Earlier this month, the National Institute on Aging (NIA) published the National Strategy for Recruitment and Participation in Alzheimer's and Related Dementia Research ̵

1; the culmination of more than two years Research to identify practical, proactive approaches that help study sites use a broader and more diverse set of volunteers for Alzheimer's and dementia research.

Picture of a healthy neuron. (Photo courtesy of the National Institute on Aging, National Institutes of Health, US Department of Health and Human Services.)

According to the NIA, the national strategy was supported by the Alzheimer's Association and the expertise and understanding of collaboration between government, private, academic, and industry representatives, as well as individuals, caregivers, and study participants.

"Our understanding of Al Zheimer's disease and related dementias in recent years. However, we still have a long way to go, "said Marie Bernard, deputy director of the office of Director NIA. and Eliezer Masliah, Director, Department of Neuroscience NIA in a statement. "One of the biggest hurdles on our path is recruiting and retaining participants in clinical trials on Alzheimer's and other dementias."

Finding older volunteers for each clinical trial is challenging. Bernard and Masliah said volunteers for clinical trials on Alzheimer's and dementia involve some significant and unique issues. "These include strict admission requirements, invasive and time-consuming procedures, the need for a study participant to have a dementia partner to accompany him on-time, the need to encourage people without symptoms, and the involvement of a wide range of participants from different backgrounds, Ethnicities and places. Driven by these challenges, the NIA's Advisory Council on Alzheimer's Disease Research, Care and Services announced its plan that organizers hope to find a way to deal with the police with many hurdles to recruiting and attachment and:

  • Increasing awareness and engagement at a broad national level
  • Establishing and improving capacity and infrastructure at study site level
  • Involving local communities and supporting participants
  • Developing an application Recruiting science

The NIA of the National Institutes of Health (NIH) stepped up its "Practical, Proactive Measures" efforts in 2016 to support research sites and researchers in recruiting and retaining a sufficient number of volunteers for a growing number of studies on Alzheimer's disease and related dementia ", says the NIA. As part of the National Plan to Combat Alzheimer's Disease, the Institute gathered stakeholders to develop a national recruitment intensification strategy to support research and clinical trials.

The NIA says the research goal of the plan requires an expansion of scientific efforts. The aim is to prevent and treat Alzheimer's disease by 2025. "However, the overarching aim of the National Strategy is to involve broad sections of the public in the research firm Alzheimer's and related dementias, with particular emphasis on under-represented communities, so that studies are conducted with one goal to better understand and ultimately heal these disorders, Individuals can be successfully and rapidly enrolled and held. "

During the course of 2017, small teams of experts met to summarize the main components of the national strategy, with a focus on three areas: national efforts, capacity building and local / diverse connections.

Apart from approving the plan, the NIA, the Steering Committee, has been working with royal groups and others will now focus on implementation and how the broad research community can work together to continue the development of the strategy.

The NIA has already launched several volunteer recruitment and retention projects: Clinical Trials on Alzheimer's and Dementia:

  • The Alzheimer's Clinical Trials Consortium, an Infrastructure for Clinical Trials designed to Accelerate and Extend Focusing on recruitment, including the establishment of a new minority outreach and recruitment team, evidence-based strategies are being used to support both centralized and local partnerships with diverse communities.
  • The Study of Diversity, Recruitment, and Retention in Aging Research will support the development of recruiting science. This announcement of funding will fund teams of researchers and community partners. The goal is to develop an infrastructure that can generate new processes, deployment practices and communication strategies to improve and improve the recruitment and retention of clinical trial staff.

Following the launch of the plan, the NIA hosted #ResearchDiversity Tuesday, October 23, to reinforce the need for diversity in clinical trials. According to the NIA, the one-day Twitter event included strategies to improve diversity in clinical trials and studies as well as acclaimed research diversity. Nearly two dozen videos by researchers in the field were shared, and messages about the need for diversity in research reached 1,400 users.

"These activities are a crucial next step in solving the complex recruitment and candidate puzzle," say Bernard and Masliah. "And we just started. We recommend that you read the strategy and think about how you can contribute to these important efforts. The broad community needs to work together to advance Alzheimer's and related dementia research. "

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With someone who develops the disease every 65 seconds in the United States, and about 5.7 million people already living with it, one might think it would be easy to volunteer for the Alzheimer's Researchers find, not so, the nation's leaders say about the study of aging, and they do something about it.

This is November 35, 1945, which has passed since President Ronald Reagan named him Alzheimer's Awareness Month. At that time there were less than two million people with the disease. Reagan himself succumbed to the ravages of Alzheimer's on June 5, 2004.

Earlier this month, the National Institute on Aging (NIA) published the National Strategy for Recruitment and Participation in Alzheimer's and Related Dementia Research – the culmination of more than two years Research to identify practical, proactive approaches that help study sites use more and more volunteers for Alzheimer's and dementia research.

Picture of a healthy neuron. (Photo courtesy of the National Institute on Aging, National Institutes of Health, US Department of Health and Human Services.)

According to the NIA, the national strategy was supported by the Alzheimer's Association and the expertise and understanding of collaboration between government, private, academic, and industry representatives, as well as individuals, caregivers, and study participants.

"Our understanding of Al Zheimer's disease and related dementias in recent years. However, we still have a long way to go, "said Marie Bernard, deputy director of the office of Director NIA. and Eliezer Masliah, Director, Department of Neuroscience NIA in a statement. "One of the biggest hurdles on our way is recruiting and retaining participants in clinical trials on Alzheimer's disease and other dementias."

Finding senior volunteers for each clinical trial is challenging, while Bernard and Masliah volunteers are clinically proven Studies on Alzheimer's and dementia involve some significant and unique problems. "These include strict admission requirements, invasive and time-consuming procedures, the need for a study participant to have a dementia partner to accompany him on-time, the need to encourage people without symptoms, and the involvement of a wide range of participants from different backgrounds, Ethnicities and places. Driven by these challenges, the NIA's Advisory Council on Alzheimer's Disease Research, Care and Services announced its plan that organizers hope to find a way to deal with the police with many hurdles to recruiting and attachment and:

  • Increasing awareness and engagement at a broad national level
  • Establishing and improving capacity and infrastructure at study site level
  • Involving local communities and supporting participants
  • Developing an application Recruiting science

The NIA of the National Institutes of Health (NIH) stepped up its "Practical, Proactive Measures" efforts in 2016 to support research sites and researchers in recruiting and retaining a sufficient number of volunteers for a growing number of studies on Alzheimer's disease and related dementia ", says the NIA. As part of the National Plan to Combat Alzheimer's Disease, the Institute gathered stakeholders to develop a national recruitment intensification strategy to support research and clinical trials.

The NIA says the research goal of the plan requires an expansion of scientific efforts. The aim is to prevent and treat Alzheimer's disease by 2025. "However, the overarching aim of the National Strategy is to involve broad sections of the public in the research firm Alzheimer's and related dementias, with particular emphasis on under-represented communities, so that studies are conducted with one goal to better understand and ultimately heal these disorders, Individuals can be successfully and rapidly enrolled and held. "

During the course of 2017, small teams of experts met to summarize the main components of the national strategy, with a focus on three areas: national efforts, capacity building and local / diverse connections.

Apart from approving the plan, the NIA, the Steering Committee, has been working with royal groups and others will now focus on implementation and how the broad research community can work together to continue the development of the strategy.

The NIA has already launched several volunteer recruitment and retention projects: Clinical Trials on Alzheimer's and Dementia:

  • The Alzheimer's Clinical Trials Consortium, an Infrastructure for Clinical Trials designed to Accelerate and Extend Studies focused on recruitment, including the establishment of a new minority outreach and recruitment team. Evidence-based strategies are used to support both centralized and local partnerships with diverse communities ,
  • The Study of Diversity, Recruitment, and Retention in Aging Research will support the development of recruiting science. This announcement of funding will fund teams of researchers and community partners. The goal is to develop an infrastructure that can generate new processes, deployment practices and communication strategies to improve and improve the recruitment and retention of clinical trial staff.

Following the launch of the plan, the NIA hosted #ResearchDiversity Tuesday, October 23, to reinforce the need for diversity in clinical trials. According to the NIA, the one-day Twitter event included strategies to improve diversity in clinical trials and studies as well as acclaimed research diversity. Nearly two dozen videos by researchers in the field were shared, and messages about the need for diversity in research reached 1,400 users.

"These activities are a crucial next step in solving the complex recruitment and candidate puzzle," say Bernard and Masliah. "And we just started. We recommend that you read the strategy and think about how you can contribute to these important efforts. To advance Alzheimer's and related dementia research requires a broad community that works together. "


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