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New study describes how some people stay thin, even if they eat like a horse



We all have a friend who seems to eat, eat and eat without spending a single pound. Unfortunately for those who want to learn this trick, it seems that this peculiarity is deeply embedded in our DNA.

New research published in the Open Access journal PLOS Genetics has investigated the search for the "genetic architecture" of skin and severe obesity in the "largest study of its kind to date". Their findings highlight some new genetic variants that are often associated with severe obesity and others associated with "healthy thinness," which may help explain why some people find it easier to stay slim than others.

Obesity epidemic refers to environmental factors such as calorie diets or lazy lifestyles ̵

1; and rightly so. However, as this study shows, genetics can also play a crucial role.

In short, obesity is a more complex situation than just eating too many burgers.

"This study shows for the first time that being healthy Thin people are usually thin because they have less exposure to genes that increase a person's chances of survival, and not because they are morally superior to how Some people like to argue, "said study leader Professor Sadaf Farooqi in a statement . "It's easy to judge and criticize people because of their weight, but science shows that things are much more complex. We have far less control over our weight than we might think.

University of Cambridge researchers in the United Kingdom studied the DNA of around 14,000 people – 1,622 thin people, 1,985 very obese people, and 10,433 people with an average body mass index (BMI) they were associated with leaner people, they determined a genetic risk score for each person.

"As expected, we had a higher value in overweight people. The genetic risk is higher than in normal weight people, which contributes to an increased risk of overweight In contrast, genetic cubes are strained, "added researcher Dr. Inês Barroso from the Wellcome Sanger Institute.

It's still unclear how these genetic variants can determine weight gain, though a number of previous studies suggest it is a question of metabolism.

In many Overweight is a growing problem throughout the world. Over 93 million people, nearly 40 percent of the US population, are classified as obese – and this number continues to rise. In the UK, this figure is around a quarter. The researchers hope that their study will help to differentiate the obesity epidemic and to agree on some new weight loss strategies.

Professor Farooqi added, "If we can find the genes that keep them from increasing, we may be able to target those genes to find new weight-loss strategies and support people who do not have that benefit."


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