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New Weight-Loss Device Aids Rats In Losing Nearly 40% Of Their Body Fat




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According to a recent global survey reported in the New England Journal of Medicine in which scientists analyzed the data from 68.5 million people between 1980 and 2015, over 710 million people worldwide are plagued by obesity problems.This number includes 107.7 million children and 603.7 million adults.Researchers thus reported that some 4 million people died of overweight or obesity-related diseases in 2015.

And according National Center for Health Statistics (NCHS) data brief, in America in 2015 and 2016, some 43% of middle-aged adults (ages 40 to 59 years), and 41% of older adults (aged 60 and older) were obese. https://www.cdc.gov/nchs/data/databriefs/db288.pdf

But University of Wisconsin-Madison scientists believe they have come up with a way to stem the tide of obesity-related disease and illness who suffer from weight problems. These scientists have created what they say is a safe and easy-to-use device that gives you nearly 40% of their body weight.

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The battery-free device, measuring less than a centimeter, generates gentle pulses from the stomach's natural motions and sends them to the vagus nerve, which left the brain and stomach.

"In vivo vagus nerve stimulation holds great promise in regulating food intake for obesity treatment," lead authors, Guang Yao and Lei Kang of the University of Wisconsin-Madison, reported in their study. Yao and Kang represent the Department of Materials Science and Engineering and the Department of Radiology, respectively. Their study was published this month in the International Science Journal Nature . "Here we present an implanted vagus nerve stimulation system that is battery-free and spontaneously responsive to stomach movement. The vagus nerve stimulation system comprises a flexible and biocompatible nanogenerator that is attached to the surface of the stomach. It generates biphasic electric pulses in response to the peristalsis of stomach.

Within 100 days of exposure to the device, the average body weight has been used in the experiment to solve the vaginal afferent fibers % of their body weight as compared to the control group. "This work correlates with stimulated organ performance through a smart, self-responsive system, and has been demonstrated to be highly effective weight control," researchers reported. "This work also provides a concept in therapeutic technology using artificial nerve signal generated from coordinated body activities."

Common non-surgical and surgical treatments for treating cancer; weight-loss drugs; and bariatric surgical procedures such as gastric bypass, biliopancreatic diversion and sleeve gastrectomy. But weight-loss drugs often have side effects as well as a high probability of weight rebound.

Researchers have said recent breakthroughs in neuromodulation for weight control have created the possibility for more effective and less invasive treatment options for obesity. "The rising healthcare standards are effective, easy to operate, and have less side effects," researchers reported. "Neuromodulation, as a Non-destructive and Reversible Therapeutic Strategy, can Manipulate Body Functions by Stimulating or Influencing Neurophysiological Signals. It has been known for a century that the vagus nerve … acts as a signal to bridge between the brain (the center of the nervous system) and the body (head, neck, thorax, and abdomen). Recent breakthroughs in neuromodulation for body weight control have provided potential opportunities for therapeutic interventions and brought renewed promises and vitality to the development of new anti-obesity strategies. "

Researches went on to say that they have already demonstrated that electrical stimulation on vagus nerve can induce multiple physiologic functions related to food intake, energy metabolism and glycemic control, all of which can result in appreciable weight loss. An implantable vagus nerve stimulation (VNS) device for weight control, Maestro, which was approved in 2015 by the U.S. Food and Drug Administration (FDA) and commercialized.

In fact, the new device does not contain any batteries, no electronics, and no complicated wiring. It relies on the stimulation of the vagus nerve when the stomach moves.

"Our correlated VNS system demonstrates outstanding weight control results, which largely outperformed other reported chronic microchips. "In addition, this correlated VNS is battery-free and less invasive compared to the bariatric surgical strategy (eg, gastric bypass, biliopancreatic diversion or sleeve gastrectomy) for weight control."

Scientists are looking at adding a switch to control the treatment in future clinical trials.

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According to a New England Journal of Medicine in which scientists analyzed the data from 68.5 million people between 1980 and 2015, over 710 million people worldwide are plagued by obesity problems.This number includes 107.7 million children and 603.7 million adults Researchers thus reported that some 4 million people died of overweight or obesity-related diseases in 2015.

And according to the Centers for Disease Control and Prevention (CDC) National Center for Health Statistics (NCHS) data letter, in America in 2015 and 2016, some 43% of middle-aged adults (ages 40 to 59 years), and 41% of older adults (aged 60 and older) were obese. https://www.cdc.gov/ nchs / data / data briefs / db288.pdf

But University of Wisconsin-Madison scientists believe they have come to terms with the condition of disease-related illness and disease. These scientists have created what they say is a safe and easily implantable weight-loss device that delivers nearly 40% of their body weight.

The battery-free device, measuring less than a centimeter, generates gentle electric pulses from the stomach's natural motions and sends them to the vagus nerve, which left the brain and stomach.

"In vivo vagus nerve stimulation holds great promise in regulating food intake for obesity treatment," lead authors, Guang Yao and Lei Kang of the University of Wisconsin-Madison, reported in their study. Yao and Kang represent the Department of Materials Science and Engineering and the Department of Radiology, respectively. Their study was published this month in the International Science Journal Nature . "Here we present an implanted vagus nerve stimulation system that is battery-free and spontaneously responsive to stomach movement. The vagus nerve stimulation system comprises a flexible and biocompatible nanogenerator that is attached to the surface of the stomach. It generates biphasic electric pulses in response to the peristalsis of stomach.

Within one hundred days of exposure to the device, the average body weight of the device has been used in the experiment to solve the vaginal afferent fibers % of their body weight as compared to the control group. "This work correlates with stimulated organ performance through a smart, self-responsive system, and has been demonstrated to be highly effective weight control," researchers reported. "This work also provides a concept in therapeutic technology using artificial nerve signal generated from coordinated body activities."

Common non-surgical and surgical treatments for treating cancer; weight-loss drugs; and bariatric surgical procedures such as gastric bypass, biliopancreatic diversion and sleeve gastrectomy. But weight-loss drugs often have side effects as well as a high probability of weight rebound.

Researchers have said recent breakthroughs in neuromodulation for weight control have created the possibility for more effective and less invasive treatment options for obesity. "The rising healthcare standards are effective, easy to operate, and have less side effects," researchers reported. "Neuromodulation, as a Non-destructive and Reversible Therapeutic Strategy, can Manipulate Body Functions by Stimulating or Influencing Neurophysiological Signals. It has been known for a century that the vagus nerve … acts as a signal to bridge between the brain (the center of the nervous system) and the body (head, neck, thorax, and abdomen). Recent breakthroughs in neuromodulation for body weight control have provided potential opportunities for therapeutic interventions and brought renewed promises and vitality to the development of new anti-obesity strategies. "

Researches went on to say that they have already demonstrated that electrical stimulation on vagus nerve can induce multiple physiologic functions related to food intake, energy metabolism and glycemic control, all of which can result in appreciable weight loss. An implantable vagus nerve stimulation (VNS) device for weight control, Maestro, which was approved in 2015 by the U.S. Food and Drug Administration (FDA) and commercialized.

In fact, the new device does not contain any batteries, no electronics, and no complicated wiring. It relies on the stimulation of the vagus nerve when the stomach moves.

"Our correlated VNS system demonstrates outstanding weight control results, which largely outperformed other reported chronic microchips. "In addition, this correlated VNS is battery-free and less invasive compared to the bariatric surgical strategy (eg, gastric bypass, biliopancreatic diversion or sleeve gastrectomy) for weight control."

Scientists are looking at adding a switch to control the treatment in future clinical trials. "This could have been a disconnected device has no impact on food intake and weight change."


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