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Home / Health / Oregon scientists part of the team testing new male birth control pill, which may have no side effects

Oregon scientists part of the team testing new male birth control pill, which may have no side effects



Professors at the Oregon Health and Science University and the University of North Carolina have just published a study on a possible new male birth control pill. The contraceptive immobilizes sperm and has no observed side effects.

"There are hormonal drugs in clinical trials that target the production of sperm" The News Observer noted, "but the previously developed affect normally affect the natural hormones in men as well as female contraceptives affect the hormones in women. "

Male monkeys from the Oregon National Primate Research Center at OHSU were the study subjects. The primates received high doses of EP055 intravenously and were then monitored for sperm mobility and other adverse side effects.

Thirty hours after an infusion, the monkey's sperm was effectively stalled and no other physical side effects were observed.

"18 days after the infusion, all [monkeys] showed signs of complete recovery," said Mary Zelinski, a research associate at the Oregon National Primate Research Center and an associate professor of obstetrics and gynecology at the OHSU School of Medicine, " which suggests that compound EP055 is indeed reversible. "

Zelinski and her co-researcher in North Carolina, Michael O. Rand, say more studies must be completed before a pill form of compound is approved for human use. Importantly, the researchers say they need to test EP055 in mating trials to definitely "determine its efficacy against pregnancy".


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