"In an infection of the spinal cord, antibody-producing immune cells migrate there and produce more antibodies, and we believe finding antibodies to enteroviruses in the spinal fluid of AFM patients means the virus is actually migrating into the spinal cord Blame for these viruses, "said Dr. Ryan Schubert, a clinical neurologist at the University of California at San Francisco and author of the new study, in an e-mail statement.
Enteroviruses are common; According to the US Centers for Disease Control and Prevention, they cause about 1
It is still unclear why virus strains are associated with paralysis in some children if they do not have the same effect in adults and why less than 1% of infected children have AFM.
"We are very excited to see why. As if, when a child reaches puberty, almost everyone is exposed to this virus, we want to know why these very few children develop this terrible outcome. " Said Lipkin. "There may be a genetic predisposition, we do not know, we also need to uncover another piece of the puzzle, which is why there is this kind of periodic eruption, it seems to be every two years, we do not understand much." Information about how EV D68 circulates and how we want to know more.
The studies are inconclusive. However, further investigation is needed. "Because of the urgency of public health However, to understand the etiology of AFM, it was important to publish these findings. "According to the CDC, since the start of follow-up in 2014, there have been nearly 600 cases [1965-9016] Most patients with AFM start the symptoms between August and October. There were 20 confirmed cases in the US in 2019.
There is no proven treatment for AFM, but knowing how AFM starts can be a first step for scientists to be better diagnostic tools and one day maybe to develop a vaccine Protect children.