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Home / Health / Scientist says only 30 minutes of your time spent twice a year could help cure Alzheimer's

Scientist says only 30 minutes of your time spent twice a year could help cure Alzheimer's




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" If you want to do something to accelerate a cure for Alzheimer's, join the Brain Health Registry, "said Dr. Michael W. Weiner [19659001ProfessorWeinergraduatedinradiologyandbiomedicalengineeringmedicinepsychiatryandneurologyfromtheUniversityofCaliforniaatUCSFwhereheistheleadinvestigatorfortheBrainHealthRegistry(BHR)andtheNationalInstitutesofHealth(NIH)fundedAlzheimer'sDiseaseNeuroimagingInitiative(ADNI)-a14-yearlong-termstudyofmorethan1500subjectsat60sitesintheUSandCanadaandoneoftheworld'slargestobservationalstudiesonAlzheimer'sdiseasewithMRIPETandbiomarkers

Dr Michael Weiner, Professor of Radiology and Biomedical Engineering, Medicine, Psychiatry and Neurology at the University of California, San Francisco (UCSF) and Senior Investigator of the Brain Health Registry (BH R).

Photo courtesy of the University of California, San Francisco (UCSF).

Weiner launched BHR five years ago as a cost-effective, scalable approach in response to ADNI's "very expensive high-tech approach to Alzheimer's disease research." The BHR's questionnaires and brain tests are tools that help researchers identify normal elderly people at risk for cognitive decline and dementia, and to provide data that will facilitate the work of other researchers.

"I've been researching for 50 years. I've been researching Alzheimer's for 25 years, "he said. "The overarching goal of our industry is to identify people at risk for mild cognitive impairment and dementia, and to develop therapies to prevent them. One reason for the sluggish research, however, is that we do not find enough volunteers for research studies. We all want. We want African Americans, Spaniards and Asians. We want workers, employees, workers, high school graduates, graduates and those with advanced degrees. We want our registration to look like America. "

Over 62,000 participants have already registered for the BHR, and scientists hope this number will increase to 100,000 or more this year. Through a series of questionnaires and brain tests that involve about 30 minutes of a participant's time twice a year, the BHR can observe and study changes in the brain over time and then use that information to accelerate brain health research. Anyone 18 years or older can join the BHR – including healthy people, people with health or memory problems, people with brain diseases, and people with or without a history of brain disease.

Since October 2014, as the BHR More than half of the respondents have returned at least once to help researchers observe brain health trends that are slowly evolving over the years.

A web-based observational research study and the first major neuroscience project to leverage online capabilities in this way, the BHR was developed to capture large amounts of data that enable researchers to become more efficient with the progression of associated cognitive changes over time Identify, evaluate and monitor neurodegenerative diseases and brain aging.

In addition to long-term data collection, the BHR has referred more than 23,000 interested participants to others. Further research studies on brain health, aging and dementia, including clinical trials.

"We want everyone to join the Brain Health Registry for a variety of reasons," Weiner said. "My own focus is on older people and people over 60, but we work together very cooperatively. We share our data with any investigator who wishes to have it. And people are interested in everything. "

Weiner said other researchers and institutions could and would have used the data for their own research in areas such as sleep disorders and cognition, autism and the aging process in general. I'm also interested in seeing what the natural aging process looks like and the The only way to do that is to compare young people to older people, and we can do that with the Brain Health Registry. "

According to Laut Weiner researchers, the UCSF is sensitive to privacy concerns, and the participants' identities only become As BHR is supervised by the UCSF, all its study activities are approved and regulated by the UCSF Institutional Review Board (IRB) or Ethics Board.

BHR participants fill out online questionnaires and questionnaires. Tests that provide researchers with the information and thus the opportunity over time, Changes in a person's health status pursue lifestyle and cognitive function. These changes could be important indicators of a person's brain health and help identify and recruit ideal candidates for medical research and future clinical trials.

Tens of millions of Americans suffer from brain disorders and the number of participants in BHR is growing every day. "As more people join and agree to completing questionnaires and brain tests, the more valuable the information they gather and the more impact researchers can have, ultimately accelerating the discovery of treatments for brain diseases such as Alzheimer's, Parkinson's and many more," Weiner

He hopes that by creating a large database of at least 100,000 prequalified potential participants, researchers hope that "making clinical trials for neurological diagnostics and treatments faster, better and more innovative. "19659001)" We are building a large pool of potential participants in clinical trials, and brain tests and questionnaires will identify those who could benefit from potential diagnostic tools or therapies, "he said." This pre-scrub candidate pool can take years of effort "If studies are faster, better and cheaper, researchers can test more theories and try out new therapeutic approaches, and the promise of breakthrough innovation is increasing – and that's what we need."

Other senior investigators at BHR are Scott Mackin, Ph.D. Associate Professor in the Department of Psychiatry at UCSF, and Rachel L. Nosheny, Ph. D., Assistant Professor of Psychiatry at UCSF.

The BHR works with the Alzheimer's Association, the Alzheimer's & # 39; s Drug Discovery Foundation, the California Department of Health, General Electric, the Global Alzheimer's Pl atform Foundation and many others and is funded by them.

] More information about joining the BHR can be found here.

The ADNI study is urgently looking for participants, Weiner said. This research study uses state-of-the-art imaging to monitor the brain levels of two proteins – tau and amyloid – that have proven to be important indicators of Alzheimer's disease. The researchers also track cognitive function through home computer testing and occasional exams and tests in a doctor's office. There are no medications involved. Participants must be:

  • between the ages of 55 and 90;
  • have memory problems with or without diagnosis of early Alzheimer's disease or mild cognitive impairment (MCI).

For more information on participating in the ADNI study, click here.

Weiner has authored 821 peer reviewed papers and 62 book chapters. He has received 19 separate research grants and received numerous awards, including the Middleton Award for Outstanding Research in Veteran Administration and the Nancy and Ronald Reagan Award for Research on the Alzheimer's Society.

Nevertheless, he is reluctant to predict treatment duration and duration / or a cure for Alzheimer's disease is found: "We can not even predict the next election. How can we predict a cure for Alzheimer's disease? Predicting things is very dangerous. There are some promising treatment attempts, so a discovery might come soon, but we just do not know. People want to be hopeful, but that's not like a skyscraper. Progress is made, but progress is slow. If you want to do something to help the field, log in to Brain Health Registry or volunteer for a trial. "

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" If you want to do something to accelerate the healing of Alzheimer's, sign up for the Brain Health Registry. Said Michael W. Weiner, MD

Professor of radiology and biomedical engineering, medicine, psychiatry and neurology at the University of California, San Francisco (UCSF), Weiner is the principal investigator of the Brain Health Registry (BHR) and National Institutes of Health (NIH) funded Alzheimer's Disease Neuroimaging Initiative (ADNI) – a 14-year longitudinal study involving more than 1,500 subjects at 60 sites in the US and Canada and one of the world's largest observational studies on MRI, PET and biomarkers for Alzheimer's disease research ,

Dr. Michael Weiner, Professor of Radiology and Biomedical Engineering, Medicine, Psychiatry and Neurology at the University of California, San Francisco (UCSF) and Principal Investigator of the Brain Health Registry (BHR).

Photo courtesy of the University of California, San Francisco (UCSF).

Weiner adopted the BHR five years ago as a cost-effective, scalable approach in response to the high-tech approach of ADNI to Alzheimer's research. The BHR's questionnaires and brain tests are tools that help researchers identify normal elderly people at risk for cognitive decline and dementia. They provide data that facilitate the work of other researchers.

"I've been researching for 50 years. I've been researching Alzheimer's for 25 years, "he said. "The overarching goal of our industry is to identify people at risk for mild cognitive impairment and dementia, and to develop therapies to prevent them. One reason for the sluggish research, however, is that we do not find enough volunteers for research studies. We all want. We want African Americans, Spaniards and Asians. We want workers, employees, workers, high school graduates, graduates and those with advanced degrees. We want our registration to look like America. "

Over 62,000 participants have already registered for the BHR, and scientists hope this number will increase to 100,000 or more this year. Through a series of questionnaires and brain tests that involve about 30 minutes of a participant's time twice a year, the BHR can observe and study changes in the brain over time and then use that information to accelerate brain health research. Everyone who is at least 18 years of age can join the BHR – including healthy people, people with health or memory problems, people with brain diseases and those with or without brain disease in family history.

Since October 2014, as the BHR More than half of respondents have returned at least once to help researchers observe brain health trends that are slowly evolving over the years.

A web-based observational research study and the first major neuroscience project to leverage online capabilities in this way, the BHR was developed to capture large amounts of data that enable researchers to become more efficient with the progression of associated cognitive changes over time Identify, evaluate and monitor neurodegenerative diseases and brain aging.

In addition to long-term data collection, the BHR has referred more than 23,000 interested participants to other research studies on brain health, aging and dementia, including clinical trials.

"We want everyone to join the Brain Health Registry for a variety of reasons," Weiner said. "My own focus is on older people and people over 60, but we work together very cooperatively. We share our data with any investigator who wishes to have it. And people are interested in everything. "

Weiner said other researchers and institutions could and would have used the data for their own research in areas such as sleep disorders and cognition, autism and the aging process in general. I'm also interested in seeing what the natural aging process looks like and the The only way to do that is to compare young people to older people, and we can do that with the Brain Health Registry. "

According to Laut Weiner researchers, the UCSF is sensitive to privacy concerns, and the participants' identities only become As BHR is supervised by the UCSF, all its study activities are approved and regulated by the UCSF Institutional Review Board (IRB) or Ethics Board.

BHR participants fill out online questionnaires and questionnaires. Tests that provide researchers with the information and thus the opportunity over time, Changes in a person's health status pursue lifestyle and cognitive function. These changes could be important indicators of a person's brain health and help identify and recruit ideal candidates for medical research and future clinical trials.

Tens of millions of Americans suffer from brain disorders and the number of participants in BHR is growing every day. "As more people join and agree to completing questionnaires and brain tests, the more valuable the information they gather and the more impact researchers can have, ultimately accelerating the discovery of treatments for brain diseases such as Alzheimer's, Parkinson's and many more," Weiner

He hopes that by creating a large database of at least 100,000 prequalified potential participants, researchers hope that "making clinical trials for neurological diagnostics and treatments faster, better and more innovative. "19659001)" We are building a large pool of potential participants in clinical trials, and brain tests and questionnaires will identify those who could benefit from potential diagnostic tools or therapies, "he said." This pre-scrub candidate pool can take years of effort "If studies are faster, better and cheaper, researchers can test more theories and try out new therapeutic approaches, and the promise of breakthrough innovation is increasing – and that's what we need."

Other senior investigators at BHR are Scott Mackin, Ph.D. Associate Professor in the Department of Psychiatry at UCSF, and Rachel L. Nosheny, Ph. D., Assistant Professor of Psychiatry at UCSF.

The BHR works with the Alzheimer's Association, the Alzheimer's & # 39; s Drug Discovery Foundation, the California Department of Health, General Electric, the Global Alzheimer's Pl atform Foundation and many others and is funded by them.

] More information about joining the BHR can be found here.

The ADNI study is urgently looking for participants, Weiner said. This research study uses state-of-the-art imaging to monitor the brain levels of two proteins – tau and amyloid – that have proven to be important indicators of Alzheimer's disease. The researchers also track cognitive function through home computer testing and occasional exams and tests in a doctor's office. There are no medications involved. Participants must be:

  • between the ages of 55 and 90;
  • have memory problems with or without diagnosis of early Alzheimer's disease or mild cognitive impairment (MCI).

For more information on participating in the ADNI study, click here.

Weiner has authored 821 peer reviewed papers and 62 book chapters. He has received 19 separate research grants and received numerous awards, including the Middleton Award for Outstanding Research in Veteran Administration and the Nancy and Ronald Reagan Award for Research on the Alzheimer's Society.

Nevertheless, he is reluctant to predict treatment duration and duration / or a cure for Alzheimer's disease is found: "We can not even predict the next election. How can we predict a cure for Alzheimer's disease? Predicting things is very dangerous. There are some promising treatment attempts, so a discovery might come soon, but we just do not know. People want to be hopeful, but that's not like a skyscraper. Progress is made, but progress is slow. If you want to do something to help the field, join the Brain Health Registry or volunteer for a trial. "


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