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Scientists succeed in destroying HIV-infected cells in a major breakthrough



Scientists have announced a potentially important breakthrough in the fight against HIV.

Researchers at Pasteur Institute in Paris say they have successfully destroyed cells infected with the virus, which are typically treated with antiretroviral drugs.

The drugs are unable to remove the virus from the body, but the medical journal Cell Metabolism yesterday published results that revealed that scientists had found a way to eliminate infected "reservoir" cells.

In a press release uploaded to EurekaAlert, a spokesman for the Institut Pasteur said: "The antiretroviral treatment used today is designed to block HIV infection but not to remove the virus from the body."

"The virus remains in reservoirs ̵

1; the CD4 T lymphocyte immune cells, the main targets of HIV."

HIV targets cells with high metabolic activity and "hijacks" their energy to proliferate.

The release states: "Thanks to metabolic activity inhibitors, researchers have succeeded in destroying these infected cells or" reservoirs "ex vivo."

It concludes by saying that research opens up the possibility of new pathways to remission, by removing the & # 39; reservoir & # 39; cells.

The next research step will be the evaluation of the potential of in vivo tested metabolic inhibitors on living organisms.

Theoretically, if the viral load is low enough to destroy the cell that hides HIV and deprives of energy that could prevent the body from spreading in the body and perhaps even wiping out, he hopes.

The study was funded by the Institut Pasteur, AmfAR (American Foundation for AIDS Research) and Sidaction.

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