Approximately half of the patients on statin prescriptions do not envisage cholesterol dropping to the desired level within two years, as new research shows. A greater reduction in low density lipoprotein cholesterol by the treatment.
However, a new study published in Heart found that half of people (51%) responded to the drugs "suboptimally" after 24 months.
University of Nottingham researchers analyzed data from 1
On average, they were 62 years old when they started treatment.
In total, 84,609 patients had a "suboptimal" response at two years and no 40% or more decrease in cholesterol.
The researchers note that a higher proportion of patients were prescribed a "sub-optimal" response with lower potency doses. co Compared to those with an "optimal" reaction.
Patients who did not reach the targeted levels were 22% more likely to develop cardiovascular disease than those who responded well.
The researchers said the study revealed "real evidence" about statins.
"These findings add to the debate on the efficacy of statin therapy and underscore the need for personalized medicine in lipid management for patients," she wrote.
Professor Metin Avkiran, Associate Medical The Director of the British Heart Foundation said: "Statins are an important and proven means of lowering cholesterol and reducing the risk of a potentially fatal heart attack or stroke.
"Although this study indicates that not everyone who is prescribed statins will manage this, their cholesterol level should be reduced sufficiently, which does not explain why.
"It may be that these people were prescribed low-dose or low-potency statins. We do not take the medication as prescribed, or they do not respond well to the type of statin prescribed.
"If you have been prescribed statins, you should take them regularly as prescribed.
"If you have concerns, you should discuss your medications with your family doctor.
Professor Helen Stokes-Lampard, chairwoman of the Royal College of GPs, said," If we prescribe medication, we must rely on patients you take for both the recommended dose and the length of time that we believe will benefit the most.
"There is extensive research showing that statin drugs are safe and effective for most people and can reduce the risk of heart attacks and strokes when prescribed accordingly – but controversy still exists in their context widespread use and its potential side effects.
Statins messaging could be one of them. "