Porphyromonas gingivalis, a key bacterium in chronic gum disease, appears to be the cause of Alzheimer's disease, researchers say.
A series of recent studies focused on the link between gum disease and Alzheimer's and Cortexyme researchers now believe their latest study depicts P. gingivalis as a tragic memory loss disease not a symptom.
"Bacteria involved in chewing gum and other illnesses have been found in the brains of people affected by Alzheimer's disease It has not been clear to date whether these bacteria have caused the disease or simply brain damage caused by the disease have been received, "reports New Scientist.
The finding, says the site, could lead to an Alzheimer's vaccine: "[A] a drug that blocks the major poisons of P. gingivalis is in major clinical trials this year, and the studies released today show that it could stop Alzheimer's and even reverse it. "
Regard Because the link between the bacteria and Alzheimer's exists, the site explains that in experimental mice that were developed for the disease, the symptoms had worsened when they had gingivitis. P. gingivalis "can cause Alzheimer's-like brain inflammation, nerve damage, and amyloid plaques in healthy mice." "
" In the new study, Cortexyme has now reported to have found the toxic enzymes ̵
And when Cortexyme gave out mice molecules that blocked gingipains," they reduced their infections, stopped amyloid production, lowered encephalitis, and even rescued damaged neurons. " Of course, there are far more people with gum disease than Alzheimer's, but the researchers believe that the disease affects people who accumulate gingipains and brain damage fast enough to symptoms during their lifetime.
At the University of Central Lancashire, UK
Cortexyme reported in October that the best of her gingipain blockers had passed initial safety tests in humans and invaded her brain, and it also seemed to improve Alzheimer's, and later this year the company will become one more extensive study of the drug, before and after the search for P. gingivalis in the cerebrospinal fluid and for cognitive improvements, "notes the site.
According to Colgate.com, signs of gum disease may occur "Gums that bleed on eating, brushing and flossing because they're swollen and tender, you may also notice that your gums are going down, and if they do, your teeth will look longer If you notice any sores in the mouth or pus between your gums and teeth, you may be at risk of having gum disease. "