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The fear can be alleviated by the regulation of intestinal bacteria



  Intestinal bacteria
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People experiencing anxiety symptoms could be helped by measures to regulate the microorganisms in their intestines with probiotic and non-probiotic foods and dietary supplements. This suggests an overview of studies published today in the journal General Psychiatry .

Anxiety symptoms are common in people with mental illness and a variety of physical disorders, especially stress-related disorders.

Previous studies have shown that up to a third of people during this time have anxiety symptoms displaying their lifespan.

Studies have increasingly shown that intestinal microbiota ̵

1; the trillions of microorganisms in the intestine that fulfill important functions in the immune system and metabolism by providing important inflammatory mediators, nutrients and vitamins – can regulate brain function through so-called "bowel function". brain axis ".

Recent research suggests that mental disorders may be treated by the regulation of gut microbiota, but there is no specific evidence to support this. Therefore, a research team of the Shanghai Mental Health Center at the Faculty of Medicine of Jiao Tong University in Shanghai to investigate whether signs of an improvement in anxiety present Ety symptoms through the regulation of intestinal microbiota

.

They reviewed 21 studies that looked at 1,503 people together.

Of the 21 studies, 14 had probiotics as interventions to control the intestinal microbiota (IRIF) and seven non-probiotic options such as adjusting the daily diet.

Probiotics are living organisms that are naturally occurring in some foods and are also referred to as "good" or "friendly" bacteria because they fight harmful bacteria and prevent them from settling in the gut. [19659005] The researchers found that probiotic supplements contained only one type of probiotics in seven studies in their analysis, two studies used a product containing two types of probiotics, and the supplements used in the other five included at least three types.

Overall, 11 of the 21 studies showed a positive effect on anxiety symptoms by regulating the gut microbiota, meaning that more than half (52%) of the studies showed this approach to b effective, although some studies that had used this approach showed no effect.

Of the 14 studies that used probiotics as an intervention, more than a third (36%) were found to be effective in reducing anxiety symptoms. While six of the remaining seven studies that used non-probiotics as interventions found them effective – an efficacy rate of 86%.

Some studies used both the IRIF approach (interventions to control the gut microbiota) and the usual treatment

Only the studies in which the treatment was used as usual and the IRIF were used as an intervention were included in the five studies where non-probiotic methods were used, positive results showing a reduction in anxiety symptoms.

Non-probiotic interventions were also more effective in the studies using only IRIF. In these studies, where only IRIF was used, 80% were found to be effective when non-probiotic interventions were applied, while only 45% were shown to be effective when probiotic interventions were applied. Probiotics interventions were possible because of a change in diet (a diverse source of energy) could affect intestinal bacteria growth more than introducing certain types of bacteria into a probiotic preparation.

Also, because some studies have introduced other types of probiotics that may have fought against each other to work effectively, and many of the intervention times used may have been too short to significantly increase the frequency of imported bacteria.

Most studies did not report serious adverse events and only four studies reported mild side effects such as dry mouth and diarrhea.

This is an observational study that as such can not prove you are causing it. In fact, the authors acknowledge some limitations, such as: B. Differences in study design, subjects, procedures, and measurements that make the data unsuitable for further analysis.

Nevertheless, the overall quality of the 21 included studies is high.

The researchers conclude: "We note that more than half of the included studies have shown that the treatment of anxiety symptoms is beneficial by regulating the gut microbiota." There are two types of interventions (probiotic and not probiotic interventions) for the regulation of the gut microbiota, and it should be emphasized that the non-probiotic interventions were more effective than the probiotic interventions. Further studies are needed to clarify this conclusion, as we can not yet perform a meta-analysis. "

They also suggest that in addition to the use of psychotropic drugs for treatment, we may also consider regulating the intestinal flora to relieve anxiety symptoms."


Probiotics could help millions of patients suffering from bipolar disorder


Further information:
Effects of Regulating the Intestinal Microbiota on Anxiety Symptoms: A Systematic Review, General Psychiatry DOI: 10.1136 / gpsych-2019-100056

Provided by
British Medical Journal




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Anxiety can be alleviated by the regulation of intestinal bacteria (2019, May 20)
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