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They have two ages, chronological and biological. Why is it important?



Before her, the equation extends over several lines and occupies most of the surface. This algorithm represents a new way of thinking about age.

"In my lab we are working on many different aging measures," Levine said. "One of the youngest is based on blood measurements that you receive at your normal medical appointment, we basically take them and combine them with different algorithms to get the phenomenon we call a phenotypic age or biological age."

That's every two ages: a chronological age, how old the calendar says it is, and a phenotypic or biological age, basically the age at which your body works relative to average fitness or health status.

"People of the Same Chronological Age" Not everyone is at the same risk of developing or even dying of cardiovascular disease or cancer, "Levine said." [the biological age] actually gives us a better idea of ​​where someone is stands for his age. "

" Chronological age is not as old as we really are. It's a superficial number, "said Professor David Sinclair, co-director of the Paul F. Glenn Center for Aging Biology at Harvard Medical School," We all age organically at different rates, depending on our genes, what we eat, how much we train and what environmental toxins we are exposed to. The biological age determines our health and ultimately our lifespan. Biological age is the number of candles we really have In the future, with the advances in our ability to control biological age, we could have even fewer candles on the cake than the previous ones.

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Levine and her team identified nine biomarkers that were recorded in a simple blood test The biomarkers include blood sugar, kidney and liver measurements as well as immune and inflammatory measures.

Levine puts these numbers into the computer and the algorithm does the rest.

People with one biological ages below their chronological ages have a lower risk of mortality, while those who grow older from a biological point of view have a higher mortality risk and may be more susceptible to the development of diseases associated with older age.

But perhaps the most important thing – unlike genetic testing results – is that these measures are changed Doctors can use this information and empower patients to change their lifestyle, diet, exercise and sleep habits, and hopefully take steps to reduce the risk and improve their biological age.

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"The most exciting thing about this research is that these things are not set in stone are, "said Levine.

"We really know a lot about changing some of these markers, and I think we get the information much earlier in the process, hopefully before anyone ever develops a disease, then they can really take steps to improve their health improve it's too late. "

Levine, who was already fascinated by aging as a young girl, even entered her own numbers into the algorithm. She was surprised by the results.

"I've always thought I was a very healthy person," she said. "I'm physically active, I eat what I think is a pretty healthy diet, and I did not find my results as good as I hope they were."

Now she's trying to sleep more and change her diet and exercise routine. "It was a wake up call," she said.

Levine works with a group to provide online access to the algorithm so that everyone can calculate their biological age, identify potential risks, and take action to support their own health in the long run.

"Nobody wants to live an extremely long life when he is in very poor health and has many chronic diseases," Levine said. By delaying the onset of disease and cognitive and physical functional problems, "people can still engage in society." "I think that's the ideal we should strive for."


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