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This new vaccine can replace oral blood thinners to reduce the risk of stroke



TOKYO: Researchers have tested a vaccine, S100A9, that could replace oral blood thinners to reduce the risk of secondary strokes from blood clots, without increasing the risk of serious bleeding or triggering an autoimmune reaction, new research.

Oral blood thinners are medicines that help with blood flow through the veins and arteries.

According to the study, people who have a stroke caused by a blood clot often need to take medicines that make their blood less clotting, which in turn prevents another stroke.

"Many stroke patients do not take their blood-thinning medications as prescribed, which makes them more likely to have another stroke, and this vaccine could someday help solve this problem because it only needs periodic injection," Hironori said Nakagami, a professor at Osaka University in Japan.

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The results published in the journal Hypertension showed that the vaccine prevents blood clots and protects the arteries of treated mice for more than two months before the formation of new blood clots.

The vaccine in mice protects against clots for more than two months without increasing the risk of bleeding or an autoimmune reaction.

In addition, it worked as well as the clopidogrel (oral blood thinner) in a large artery.

Developing a vaccine to replace and / or supplement daily oral medications could, according to Nakagami, save many lives and help prevent both secondary strokes and possibly heart attacks.

"… between mice and humans there are differences in the way the vaccine is recognized by the immune system, we should be able to overcome such problems and believe that this vaccine is a promising strategy in He also noted that "secondary prevention of stroke offers.


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