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UNM researchers develop vaccine for Alzheimer's



University of New Mexico researchers have developed a vaccine that could prevent Alzheimer's disease. PHD student Nicole Maphis, who participates in the UNM's Biomedical Sciences graduate program, says, "We are excited about this finding because it suggests that we can use the body's immune system to make antibodies to these complications and these antibodies to actually bind and eliminate these tau complications. "Maphis and Kiran Bhaskar, a professor at the UNM's Department of Molecular Genetics and Microbiology, found that the vaccine was given to mice, developed antibodies that removed the tau protein from their brains, and the reaction took months. Then Maphis and Bhaskar tested the animals in a series of labyrinthine tests. Mice receiving the vaccine performed significantly better than those who did not. MRI scans showed that the vaccinated animals had lower brain shrinkage, indicating that the vaccine prevented the death of neurons. Maphis says, "These results confirm that targeted dew confusion with the help of a vaccine intervention can remedy memory dysfunction and prevent the death of neurons." UNM scientists David Peabody and Bryce Chackerian developed the Human Papillomavirus vaccine (found in the brains of Alzheimer's patients). In the future, Bhaskar would like to receive funding for the commercialization of this vaccine for the development of an injection that could someday be tested in Alzheimer's patients. Bhaskar is optimistic that it will receive them The funding of the vaccine from a federal research grant for small businesses to advance the research project. However, the manufacture of this medicine could potentially cost millions of dollars and take decades.

Researchers at the University of New Mexico have developed a vaccine that could prevent Alzheimer's disease.

Doctoral student Nicole Maphis, who is participating in the UNM's Biomedical Sciences graduate program, says, "We are pleased with these results because they suggest that we can use the body's immune system to make antibodies against these complications, and that Antibodies actually bind and eliminate these tau complications. "

Maphis and Kiran Bhaskar, a professor at UNM The Department of Molecular Genetics & Microbiology found that mice developed antibodies to the vaccine when they removed the tau protein from their brains and stopped the reaction for months.

Then Maphis and Bhaskar tested the animals in a battery of labyrinthine tests. Mice receiving the vaccine performed significantly better than those who did not. MRI scans showed that the vaccinated animals had lower brain shrinkage, indicating that the vaccine prevented the death of neurons.

Maphis says, "These results confirm that targeted dew entrapment using a vaccine can repair memory dysfunction and prevent the death of neurons."

UNM scientists David Peabody and Bryce Chackerian developed the vaccine dengue virus, hepatitis B, and human papillomavirus (found in the brain of Alzheimer's disease patients).

In the future, Bhaskar intends to receive funding for the marketing of this vaccine for injection, which could one day be tested on human patients Alzheimer's.

Bhaskar is confident that she will finance the vaccine from a government research fellowship for small businesses to advance the research project.

However, the manufacture of this medicine could potentially cost millions of dollars and take decades.

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