LONDON, Jan. 11 – New UK research has found that wearing extra body fat, especially around the waist, may be associated with a smaller brain size, suggesting a higher risk of dementia.
Carrying out research by Loughborough University, the new study examined 9,652 adults with a mean age of 55 and used magnetic resonance imaging (MRI) to measure brain volume for white and gray matter.
Examining the Possible Impact of Transport In addition to these brain volumes, researchers weighed the obesity of the participants by measuring the body mass index (BMI), a weight-to-height ratio, by dividing a person's weight by the square of their height Height was calculated. People with a BMI above 30.0 are considered obese.
Then, the waist-to-hip ratio of the participants was measured, which was determined by dividing the waist circumference by the hip circumference. People with larger bellies compared to their hips have a higher ratio, with men over 0.90 and women over 0.85 considered to be centrally obese.
The results published in the journal Neurology showed this after adaptation. In other factors that can affect brain volume, such as age, physical activity, smoking, and hypertension, participants with a high BMI had a slightly lower volume on gray matter as such with a healthy BMI.
High BMI and waist-to-hip ratio showed an even lower volume of gray matter than participants without a high waist-to-hip ratio.
There were no significant differences in white matter brain volume.
"Previous research has linked deceleration of the brain to memory deterioration and higher dementia risk, but research into whether additional body fat protects or damages brain size has not been conclusive," said study author Mark Hamer, PhD. "Our research looked at a large group of people and found that obesity, especially in the middle, could be associated with brain shrinkage."
Gray matter contains most of the nerve cells of the brain and includes brain regions involved in self-control and muscle control and sensory perception. White matter contains nerve fiber bundles that connect different regions of the brain.
"While in our study, obesity was found mostly in the middle, this was associated with lower brain volumes of gray matter, however, it is unclear whether abnormalities in the brain structure lead to obesity. Obesity leads to these changes in the brain," said Hamer. "We also found links between obesity and shrinkage in certain regions of the brain. This requires further research, but it may be that one day the regular measurement of BMI and waist-to-hip ratio can determine the health of the brain. "- AFP-Relaxnews