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What everyone should know about the antibiotic crisis



The use of antibiotics is at a high level worldwide. But what does that mean for the future?

The discovery of penicillin in 1929 was a turning point. Since then, millions of people have received antibiotics to effectively treat serious illnesses.

But overuse has become a major problem. There are dangers of too much antibiotics, but there are ways in which anyone can help.

Antibiotics can be life-saving. But excessive use can lead to a real problem: antibiotic resistance. It happens when bacteria change to resist the effects of medicine.

"People need to remember that bacteria have been on this earth for 4 billion years," Dr. Amesh Adalja from the University of Pittsburgh. "So it's no surprise that bacteria can outsmart us."

Experts believe that about one-third of US-prescribed antibiotics are unnecessary. And a new report, which looked at consumption in 76 countries, found that the use of antibiotics increased by 39 percent between 2000 and 201

5.

Researchers estimate that up to 10 million deaths worldwide will be due to antimicrobial resistance by 2050 [19659008] "We are running out of antibiotics and in certain scenarios we are now busy telling a patient that we offer them nothing can, "Adalja said.

So what can you do? First, if you use an antibiotic, do not stop taking the drug early. This makes it easier for the bacteria to multiply and become resistant. Never use "left over" antibiotics. When used after their due date, they are more likely to cause resistance. And trust your doctor if he or she says you do not need an antibiotic.

"One of the main reasons, at least in this country, is the fact that the public is beginning to demand antibiotics for every cough, cold or virus disease, regardless of the fact that antibiotics have no effect on viruses," Adalja said ,

Researchers found that the increase in antibiotic use was most dramatic in low-income and middle-income countries. 19659004] SUMMARY OF RESEARCH
ANTIBIOTICS CRISIS: WHAT YOU NEED TO KNOW
REPORT # 2541

BACKGROUND: Antibiotic resistance is one of the world's most pressing health problems. Every time a person takes antibiotics, sensitive bacteria are killed, but resistant bacteria can grow and multiply. At least 30 percent of ambulant antibiotics are unnecessary, so no antibiotic is needed at all. The bulk of this unnecessary use is for acute respiratory problems such as colds, bronchitis, sore throat caused by viruses and even some sinus and ear infections. Excessive use of antibiotics is an important variable cause of the increase in drug-resistant bacteria. Excessive use and abuse of antibiotics threatens the usefulness of these important drugs. Reducing the inappropriate use of antibiotics is a key strategy for controlling antibiotic resistance. Antibiotic resistance in children and older adults is particularly worrying as these age groups have the highest rates of antibiotic use. Antibiotic resistance can cause significant suffering to people with frequent infections who used to be easily treated with antibiotics. When antibiotics are not effective, infections often last longer, cause more serious illnesses, require more visits to the doctor or longer hospital stays, and involve more expensive and toxic drugs. Some resistant infections can even lead to death.
(Source: https://www.cdc.gov/antibiotic-use/community/about/fast-facts.html)

ANTIBIOTICS: WHAT WE SHOULD KNOW: colds, flu, sore throat, bronchitis and many sinuses and ear infections are caused by viruses. Antibiotics do not help against viruses. Antibiotics are not helpful for the vast majority of common respiratory infections. Antibiotics cure bacterial infections, not viral infections, nor do they prevent other people from getting the disease or feeling better. Taking antibiotics for a virus can do more harm than good. It increases the risk of getting an antibiotic-resistant infection later. It also kills the healthy bacteria in the gut and allows more harmful bacteria such as C. difficile to grow in its place. Although this infection is more common in hospitals, it also occurs in clinics outside the hospital. Antibiotics cause 1 in 5 emergency medical visits for adverse drug reactions and are the leading cause of emergency medical attention for adverse drug reactions in children under 18 years of age. It is important to only use antibiotics to fight bacterial infections as they may present a risk of harmful side effects and antibiotic-resistant infections for you or your child.
(Source: https://www.cdc.gov/antibiotic-use/community/about/should-know.html)



SCIENTIST BREAKTHROUGH: Scientists who have been working on the development of a groundbreaking new antibiotic made significant progress in the development of commercially viable drug treatments. They created two simplified synthetic versions of the substance that are equally effective in killing super bacteria such as MRSA as a natural form. The breakthrough of researchers at the University of Lincoln, UK, is another important step in realizing the potential of teixobactin in supporting the global fight against antibiotic-resistant pathogens. Teixobactin is a recently discovered natural antibiotic that many in the international scientific community believe could lead to the creation of the first commercially viable new antibiotic in 30 years. Ishwar Singh, MD, a specialist in novel drug design and development at the Lincoln School of Pharmacy, said: "When teixobactin was discovered, it was groundbreaking as a new antibiotic that kills bacteria with no detectable resistance, including super-bacteria MRSA: We have been looking for a way to simplify design while maintaining high potency against resistant bacteria. "
(Source: https://phys.org/news/2017-11-scientists-significant-breakthrough-road- superbug-killing.html)


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