Science continues to work to help people realize their dreams of staying young forever, or at least looking that way. A new genetic experiment conducted at the University of Alabama in Birmingham promises to reverse two of the most common and visible effects of aging. According to scientific research published on Friday in the journal Cell Death & Disease the researchers succeeded in switching back the clock on older, wrinkled and balding mice when they performed the age reversal experiment
Finished the experiment For example, mice that previously suffered from heavily wrinkled skin and spotty, thinning hair looked identical to their younger, smooth-skinned, full-haired counterparts, summarizing the experiment of Science Daily .
"To our knowledge, this observation is unprecedented," said Keshav Singh, the study's senior researcher and professor of genetics at the University of Alabama at Birmingham Medical School, cited by Science Daily .
What did Singh and his team of geneticists do to achieve this seemingly amazing result? They simply "switched off" a gene in the mice that caused a malfunction of the cellular mitochondria. When the dysfunction was reversed, the aging symptoms, according to a UAB review of work
Mitochondria are specialized structures, known as organelles, that live in each cell and provide much of the energy that each cell consumes in the human body or the body of an animal or plant, according to Live Science . In fact, it is believed that the many mitochondria living in each cell provide up to 90 percent of the energy consumed by the cell. When mitochondria become bad, so do the cells and die.
After causing mitochondrial dysfunction in the mice, the UAB scientists observed that the mice developed severe aging symptoms within a few weeks, especially skin wrinkles and hair loss. Restoring the function of injured mouse mitochondria in the UAB experiment eradicated the effects of aging and restored the mice's youthful appearance.
"This mouse model should provide an unprecedented opportunity for the development of preventive and therapeutic drug development strategies to enhance mitochondrial functions for the treatment of age-related skin and hair pathology and other human diseases in which mitochondrial dysfunction plays a significant role, as Singh News India
says experiments could eventually lead to new drugs and other therapies that would restore a youthful appearance in aging people and in laboratory mice.